Human Genomics - 2022

73 articles | Last updated: 2025-12-03 14:12:57
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T A T A T A T A
Digital PCR-based evaluation of nucleic acid extraction kit performance for the co-purification of cell-free DNA and RNA
Circulating miR-320a-3p and miR-483-5p level associated with pharmacokinetic–pharmacodynamic profiles of rivaroxaban
Identification of a minimum number of genes to predict triple-negative breast cancer subgroups from gene expression profiles Italian
Whole‐exome sequencing of a Saudi epilepsy cohort reveals association signals in known and potentially novel loci
Preimplantation genetic testing for aneuploidy: challenges in clinical practice
Correction: Whole-exome sequencing of BRCA-negative breast cancer patients and case–control analyses identify variants associated with breast cancer susceptibility
Comprehensive characterization of putative genetic influences on plasma metabolome in a pediatric cohort
Pan-cancer illumination of TRIM gene family reveals immunology regulation and potential therapeutic implications
The bridge-like lipid transfer protein (BLTP) gene group: introducing new nomenclature based on structural homology indicating shared function
Phenotypic findings and pregnancy outcomes of fetal rare autosomal aneuploidies detected using chromosomal microarray analysis
Lack of association of TP73 rare variants with amyotrophic lateral sclerosis in a Chinese cohort European population
The integration of large-scale public data and network analysis uncovers molecular characteristics of psoriasis
Whole-exome sequencing of BRCA-negative breast cancer patients and case–control analyses identify variants associated with breast cancer susceptibility
Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant
The importance of being the HGNC
Differential upregulation of AU-rich element-containing mRNAs in COVID-19
Mutation in XPO5 causes adult-onset autosomal dominant familial focal segmental glomerulosclerosis
De novo and inherited variants in coding and regulatory regions in genetic cardiomyopathies
Placing human gene families into their evolutionary context
A review on the application of the exposome paradigm to unveil the environmental determinants of age-related diseases
Integrated proteomic and metabolomic modules identified as biomarkers of mortality in the Atherosclerosis Risk in Communities study and the African American Study of Kidney Disease and Hypertension
De novo mutations within metabolism networks of amino acid/protein/energy in Chinese autistic children with intellectual disability
Copy number variant analysis for syndromic congenital heart disease in the Chinese population
DUSP5 and PHLDA1 mutations in mature cystic teratomas of the ovary identified on whole-exome sequencing may explain teratoma characteristics
CRISPR-Cas9-mediated functional dissection of the foxc1 genomic region in zebrafish identifies critical conserved cis-regulatory elements
Biallelic mutations of TTC12 and TTC21B were identified in Chinese patients with multisystem ciliopathy syndromes
rs2013278 in the multiple immunological-trait susceptibility locus CD28 regulates the production of non-functional splicing isoforms
Nidogen-1 could play a role in diabetic kidney disease development in type 2 diabetes: a genome-wide association meta-analysis
Analysis on in vitro effect of lithium on telomere length in lymphoblastoid cell lines from bipolar disorder patients with different clinical response to long-term lithium treatment
Pharmacogenomics implementation in cardiovascular disease in a highly diverse population: initial findings and lessons learned from a pilot study in United Arab Emirates
Circular RNA hsa_circ_0000915 promotes propranolol resistance of hemangioma stem cells in infantile haemangiomas
J’Accuse….. Or The Plight of pro-bono Volunteer Scientists in Academic Publishing
Novel clinical, molecular and bioinformatics insights into the genetic background of autism
Immune dysregulation associated with co-occurring germline CBL and SH2B3 variants
De novo disruptive heterozygous MMP21 variants are potential predisposing genetic risk factors in Chinese Han heterotaxy children Chinese Han
Identification of recurrent variants implicated in disease in bicuspid aortic valve patients through whole-exome sequencing
Construction of the coexpression network involved in the pathogenesis of thyroid eye disease via bioinformatics analysis
Validating and automating learning of cardiometabolic polygenic risk scores from direct-to-consumer genetic and phenotypic data: implications for scaling precision health research previously reported genome-significant findings in Europeans
Characterization of ACE2 naturally occurring missense variants: impact on subcellular localization and trafficking
Maternal obesity alters methylation level of cytosine in CpG island for epigenetic inheritance in fetal umbilical cord blood
On the relationship between tripartite motif-containing 22 single-nucleotide polymorphisms and COVID-19 infection severity
SCP2 variant is associated with alterations in lipid metabolism, brainstem neurodegeneration, and testicular defects
Expanding ACMG variant classification guidelines into a general framework
1029 genomes of self-declared healthy individuals from India reveal prevalent and clinically relevant cardiac ion channelopathy variants
Noninvasive fetal genotyping of single nucleotide variants and linkage analysis for prenatal diagnosis of monogenic disorders
Epigenetics may characterize asymptomatic COVID-19 infection
Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1
A review of deep learning applications in human genomics using next-generation sequencing data
RNA modification-related variants in genomic loci associated with body mass index
Alternative transcription start sites contribute to acute-stress-induced transcriptome response in human skeletal muscle
Identification of phenylketonuria patient genotypes using single-gene full-length sequencing Chinese
Genetic etiology and clinical challenges of phenylketonuria
Human adaptation to high altitude: a review of convergence between genomic and proteomic signatures
From COVID to fibrosis: lessons from single-cell analyses of the human lung
COVID-19 2022 update: transition of the pandemic to the endemic phase
Genomic supremacy: the harm of conflating genetic ancestry and race continental ancestry; genetic ancestry; racial corrections; race; racialized inequities
Retraction Note: lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells
Evaluating standards for ‘serious’ disease for preimplantation genetic testing: a multi-case study on regulatory frameworks in Japan, the UK, and Western Australia
Integrative analysis of multi-omics data to detect the underlying molecular mechanisms for obesity in vivo in humans
Cross talk between RNA modification writers and tumor development as a basis for guiding personalized therapy of gastric cancer
Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis
The role of m6A methylation in osteosarcoma biological processes and its potential clinical value
Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population
Variants in genes related to development of the urinary system are associated with Mayer–Rokitansky–Küster–Hauser syndrome gnomAD East Asian populations; Beijing, China
Examining key factors impact on health science students’ intentions to adopt genetic and pharmacogenomics testing: a comparative path analysis in two different healthcare settings Greeks (Europe; Christian); Greeks and Malays (with regional labels 'Europe' and 'Asia' and religious labels 'Christian' and 'Mu
Enhancer promoter interactome and Mendelian randomization identify network of druggable vascular genes in coronary artery disease
From shallow to deep: some lessons learned from application of machine learning for recognition of functional genomic elements in human genome
Frequencies of CYP2D6 genetic polymorphisms in Arab populations
A glycolysis-related two-gene risk model that can effectively predict the prognosis of patients with rectal cancer
Why are keratins important?
A framework for research into continental ancestry groups of the UK Biobank European ancestry; non-white British
Contribution of 3D genome topological domains to genetic risk of cancers: a genome-wide computational study
Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders