Human Genomics - 2018

52 articles | Last updated: 2025-12-03 14:12:57
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Identification of drug repurposing candidates based on a miRNA-mediated drug and pathway network for cardiac hypertrophy and acute myocardial infarction
Trans-activation-based risk assessment of BRCA1 BRCT variants with unknown clinical significance
Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine
Bayesian variable selection for parametric survival model with applications to cancer omics data
Multiple genotype–phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population Korean population
Link between short tandem repeats and translation initiation site selection
Identification of gross deletions in FBN1 gene by MLPA
Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea
Architecture of polymorphisms in the human genome reveals functionally important and positively selected variants in immune response and drug transporter genes
Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing
Secondary findings in 421 whole exome-sequenced Chinese children Chinese
Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes
Forward and reverse mutations in stages of cancer development
BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population
The impact of genome-wide association studies on biomedical research publications
Associations of high-altitude polycythemia with polymorphisms in PIK3CD and COL4A3 in Tibetan populations
A new bioinformatics tool to help assess the significance of BRCA1 variants
A novel LRAT mutation affecting splicing in a family with early onset retinitis pigmentosa
Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients
Abundance of clinical variants in exons included in multiple transcripts
Caution needs to be taken when assigning transcription start sites to ends of protein-coding genes: a rebuttal
The tale of histone modifications and its role in multiple sclerosis
Computational analysis of mRNA expression profiling in the inner ear reveals candidate transcription factors associated with proliferation, differentiation, and deafness
Oxidative stress-induced chromosome breaks within the ABL gene: a model for chromosome rearrangement in nasopharyngeal carcinoma
Associations between hypertension and the peroxisome proliferator-activated receptor-δ (PPARD) gene rs7770619 C>T polymorphism in a Korean population
Integrating rare genetic variants into pharmacogenetic drug response predictions
Mutational analysis of epidermal and hyperproliferative type I keratins in mild and moderate psoriasis vulgaris patients: a possible role in the pathogenesis of psoriasis along with disease severity
Nonparametric approaches for population structure analysis
Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure
Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading
Molecular characterization of exonic rearrangements and frame shifts in the dystrophin gene in Duchenne muscular dystrophy patients in a Saudi community
Genome-scale portrait and evolutionary significance of human-specific core promoter tri- and tetranucleotide short tandem repeats
The development of large-scale de-identified biomedical databases in the age of genomics—principles and challenges
Tensions in ethics and policy created by National Precision Medicine Programs
Public attitudes in Japan toward participation in whole genome sequencing studies
Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment
Large-scale discovery of previously undetected microRNAs specific to human liver
Transcription start sites at the end of protein-coding genes
Abstracts from the Human Genome Meeting 2018
2-deoxy-2-[18]fluoro-D-glucose PET/CT (18FDG PET/CT) may not be a viable biomarker in Pompe disease
Including all voices in international data-sharing governance
Attitudes of stakeholders in psychiatry towards the inclusion of children in genomic research
A hypomorphic inherited pathogenic variant in DDX3X causes male intellectual disability with additional neurodevelopmental and neurodegenerative features
Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level
Insights about genome function from spatial organization of the genome
APPLaUD: access for patients and participants to individual level uninterpreted genomic data
The genetic structure of the Belgian population
Meeting report of the 2017 KidGen Renal Genetics Symposium
Beyond genomics: understanding exposotypes through metabolomics
Identification of compound heterozygous variants in the noncoding RNU4ATAC gene in a Chinese family with two successive foetuses with severe microcephaly
Identify Down syndrome transcriptome associations using integrative analysis of microarray database and correlation-interaction network
Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease