Human Genetics - 2012

121 articles | Last updated: 2025-12-03 14:12:56
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T A T A T A T A
Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population
Genetic association suggests that SMOC1 mediates between prenatal sex hormones and digit ratio
Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity
Transmission ratio distortion: review of concept and implications for genetic association studies
Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans
Linkage analysis of a large African family segregating stuttering suggests polygenic inheritance African
A large-scale meta-analysis of the association between the ANKK1/DRD2 Taq1A polymorphism and alcohol dependence
Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women’s Health Initiative SHARe Study African-American; Hispanic
A non-synonymous SNP in the NOS2 associated with septic shock in patients with sepsis in Chinese populations
TNFAIP3 gene polymorphisms confer risk for Behcet’s disease in a Chinese Han population
Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population
Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women
Variants in GATA4 are a rare cause of familial and sporadic congenital diaphragmatic hernia
Identification of COL6A2 mutations in progressive myoclonus epilepsy syndrome
Identification of genetic associations of SP110/MYBBP1A/RELA with pulmonary tuberculosis in the Chinese Han population Chinese Han population
Genome-wide investigation of gene–environment interactions in colorectal cancer
Exome-based linkage disequilibrium maps of individual genes: functional clustering and relationship to disease
Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study
Positive natural selection of TRIB2, a novel gene that influences visceral fat accumulation, in East Asia
Synergistical effect of 20-HETE and high salt on NKCC2 protein and blood pressure via ubiquitin–proteasome pathway
Leon E. Rosenberg and Diane Drobnis Rosenberg: Human Genes and Genomes: Science, Health, Society
Assessment of systematic effects of methodological characteristics on candidate genetic associations
A dominant-negative mutation of HSF2 associated with idiopathic azoospermia
Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans Europeans
The population genetics of the Jewish people
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG)
David Goldman: Our genes, our choices
Association between variants of EXT2 and type 2 diabetes: a replication and meta-analysis
Linkage disequilibrium pattern and age-at-diagnosis are critical for replicating genetic associations across ethnic groups in leprosy
Identity-by-descent-based heritability analysis in the Northern Finland Birth Cohort
Characterization of CCDC28B reveals its role in ciliogenesis and provides insight to understand its modifier effect on Bardet–Biedl syndrome
Familial prostate cancer and HOXB13 founder mutations: geographic and racial/ethnic variations
Novel association of a PROC variant with ischemic stroke in a Chinese Han population
Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD
Association between TNFRSF11B gene polymorphisms and history of ischemic stroke in Italian diabetic patients
Investigation of genetic risk factors for chronic adult diseases for association with preterm birth
The success of pharmacogenomics in moving genetic association studies from bench to bedside: study design and implementation of precision medicine in the post-GWAS era
A genome-wide association study of breast cancer in women of African ancestry women of African ancestry
VKORC1 rs2359612C allele is associated with increased risk of coronary artery disease in the presence of coronary calcification
Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection
Study designs and methods post genome-wide association studies
A Bayesian ensemble approach with a disease gene network predicts damaging effects of missense variants of human cancers
Complement component 4 copy number variation and CYP21A2 genotype associations in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Human subtelomeric copy number gains suggest a DNA replication mechanism for formation: beyond breakage–fusion–bridge for telomere stabilization
Genome-wide association study of glioma and meta-analysis
A beginners guide to SNP calling from high-throughput DNA-sequencing data
Genetics of familial forms of thrombocytopenia
Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2
Causation and causal inference for genetic effects
Cathepsin B SNPs elevate the pathological development of oral cancer and raise the susceptibility to carcinogen-mediated oral cancer
Two-stage association study in Chinese Han identifies two independent associations in CCR1/CCR3 locus as candidate for Behçet’s disease susceptibility Chinese Han
Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset
Network medicine: linking disorders
Genome-wide analysis of copy number variations reveals that aging processes influence body fat distribution in Korea Associated Resource (KARE) cohorts
Mutations in the sarcosine dehydrogenase gene in patients with sarcosinemia
Heritability in the genome-wide association era
Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness
Genetic variation in MDR1, LPL and eNOS genes and the response to atorvastatin treatment in ischemic stroke
Influences of FTO gene on onset age of adult overweight
Further characterization of ATP6V0A2-related autosomal recessive cutis laxa
Integration of biological networks and pathways with genetic association studies
Personalized medicine using DNA biomarkers: a review
Challenges and opportunities in genome-wide environmental interaction (GWEI) studies
Risk estimation and risk prediction using machine-learning methods
Novel neurodevelopmental information revealed in amniotic fluid supernatant transcripts from fetuses with trisomies 18 and 21
Strong purifying selection against gene conversions in the trypsin genes of primates
Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary tract malformations
The role of phenotype in gene discovery in the whole genome sequencing era
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium
Identification of germline genomic copy number variation in familial pancreatic cancer
Recommendations for ethical approaches to genotype-driven research recruitment
Genome-wide genetic associations with IFNγ response to smallpox vaccine
Promoter variants in the MSMB gene associated with prostate cancer regulate MSMB/NCOA4 fusion transcripts
Serum vitamins A and E as modifiers of lipid trait genetics in the National Health and Nutrition Examination Surveys as part of the Population Architecture using Genomics and Epidemiology (PAGE) study
Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma
The role of large pedigrees in an era of high-throughput sequencing
Evaluation of PRDM9 variation as a risk factor for recurrent genomic disorders and chromosomal non-disjunction
Genetic markers of ovarian follicle number and menopause in women of multiple ethnicities
Genome-wide association analysis of circulating vitamin D levels in children with asthma
The distinct and overlapping phenotypic spectra of FOXP1 and FOXP2 in cognitive disorders
Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships
U-statistics in genetic association studies
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients
Reduced interferon (IFN)-α conditioned by IFNA2 (−173) and IFNA8 (−884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality
The genetics of addiction
Mouse models of SMA: tools for disease characterization and therapeutic development
The genetics of the opioid system and specific drug addictions
Epidemiology of substance use disorders
Genetics of smoking and depression
A common genetic network underlies substance use disorders and disruptive or externalizing disorders
The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption
Premature to conclude no genetic basis to the association between smoking and major depressive disorder
McKinlay Gardner RJ, Sutherland GR, Shaffer LG: Chromosome abnormalities and genetic counselling
Randall H. Morse (ed.): Chromatin remodelling: methods and protocols
Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases
Genomic rearrangements at the FRA2H common fragile site frequently involve non-homologous recombination events across LTR and L1(LINE) repeats
Increased risk of stroke in oral contraceptive users carried replicated genetic variants: a population-based case–control study in China
Erratum to: Association between gout and polymorphisms in GCKR in male Han Chinese Han Chinese
Using graded response model for the prediction of prostate cancer risk
A splice site mutation in a gene encoding for PDK4, a mitochondrial protein, is associated with the development of dilated cardiomyopathy in the Doberman pinscher
Loss-of-function mutations in filaggrin gene associate with psoriasis vulgaris in Chinese population
Coexisting mutations/polymorphisms of the long QT syndrome genes in patients with repaired Tetralogy of Fallot are associated with the risks of life-threatening events
Adaptive evolution of loci covarying with the human African Pygmy phenotype
Association between gout and polymorphisms in GCKR in male Han Chinese
The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer’s disease
Genetic variants of the MRC1 gene and the IFNG gene are associated with leprosy in Han Chinese from Southwest China
NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy
Genome-wide two-locus epistasis scans in prostate cancer using two European populations European populations
Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia
Evolutionary genetics of the human Rh blood group system
Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations
Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls
Genetics of dopamine receptors and drug addiction
Drosophila melanogaster as a model to study drug addiction
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes
Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry European and Ashkenazi Jewish ancestry; Ashkenazi Jewish ancestry
Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines
The human lactase persistence-associated SNP −13910*T enables in vivo functional persistence of lactase promoter–reporter transgene expression
A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease
A functional variant of the collagen type III alpha1 gene modify risk of sporadic intracranial aneurysms
Unraveling the genetic component of systemic sclerosis