Human Genetics - 2004

182 articles | Last updated: 2025-12-03 14:12:56
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T A T A T A T A
Current status of the E23K Kir6.2 polymorphism: implications for type-2 diabetes
Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis
Expression studies of mutations underlying Taiwanese Hunter syndrome (mucopolysaccharidosis type II)
Oligogenic combinations associated with breast cancer risk in women under 53�years of age
Ocular refraction: heritability and genome-wide search for eye morphometry traits in an isolated Sardinian population
The (GT)n polymorphism and haplotype of the COL1A2 gene, but not the (AAAG)n polymorphism of the PTHR1 gene, are associated with bone mineral density in Chinese Chinese
Association of ?2-HS glycoprotein (AHSG, fetuin-A) polymorphism with AHSG and phosphate serum levels
Confirmation of the HPCX prostate cancer predisposition locus in large Utah prostate cancer pedigrees
Mutational hot spot in the DSPP gene causing dentinogenesis imperfecta type II
The USH1C 216G?A splice-site mutation results in a 35-base-pair deletion
Variation in meiotic recombination frequencies among human males
Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L
Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader?Willi syndrome
An atypical form of erythrokeratodermia variabilis maps to chromosome 7q22
Mutations
Complex segregation analysis reveals a multigene model for lung cancer
A novel ARH splice site mutation in a Mexican kindred with autosomal recessive hypercholesterolemia
Mitochondrial GTPase mitofusin 2 mutation in Charcot?Marie?Tooth neuropathy type 2A
The impact of MECP2 mutations in the expression patterns of Rett syndrome patients
Linkage disequilibrium between microsatellite markers in the Swedish Sami relative to a worldwide selection of populations
Hereditary prostate cancer in Finland: fine-mapping validates 3p26 as a major predisposition locus
A novel 5q11.2 deletion detected by microarray comparative genomic hybridisation in a child referred as a case of suspected 22q11 deletion syndrome
A new locus for nonsyndromic deafness DFNB49 maps to chromosome 5q12.3-q14.1
Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease
Diet and the frequency of the alanine:glyoxylate aminotransferase Pro11Leu polymorphism in different human populations
Novel and recurrent mutations in the laminin-5 genes causing lethal junctional epidermolysis bullosa: molecular basis and clinical course of Herlitz disease
Co-segregation and heteroplasmy of two coding-region mtDNA mutations within a matrilineal pedigree
Non-recurrent 17p11.2 deletions are generated by homologous and non-homologous mechanisms
Linkage disequilibrium mapping in the Newfoundland population: a re-evaluation of the refinement of the Bardet?Biedl syndrome 1 critical interval
Confirmation and refinement of a genetic locus of congenital motor nystagmus in Xq26.3-q27.1 in a Chinese family
RGD-containing fibrillin-1 fragments upregulate matrix metalloproteinase expression in cell culture: A potential factor in the pathogenesis of the Marfan syndrome
Hereditary hemorrhagic telangiectasia: ENG and ALK-1 mutations in Dutch patients Dutch
Y chromosome haplogroups of elite Ethiopian endurance runners
TP53 haplotype-based analysis and incidence of post-angioplasty restenosis
The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis
Mutations of RAI1, a PHD-containing protein, in nondeletion patients with Smith-Magenis syndrome
The human T locus and spina bifida risk
Mutational analysis of OGG1, MYH, MTH1 in FAP, HNPCC and sporadic colorectal cancer patients: R154H OGG1 polymorphism is associated with sporadic colorectal cancer patients
Emery A.E.H., Muntoni F. (eds): Duchenne muscular dystrophy.
Genome-wide linkage analysis replicates susceptibility locus for fasting plasma triglycerides: NHLBI Family Heart Study
Francis Galton: Pioneer of heredity and biometry (2003)
Mapping genomic deletions down to the base: a quantitative copy number scanning approach used to characterise and clone the breakpoints of a recurrent 7p14.2p15.3 deletion
Two linked polymorphic mutations (A(TA)7TAA and T-3279G) of UGT1A1 as the principal cause of Gilbert syndrome
FISH diagnosis of the common 57-kb deletion in CTNS causing cystinosis
A large MSH2 Alu insertion mutation causes HNPCC in a German kindred
Positive selection in MAOA gene is human exclusive: determination of the putative amino acid change selected in the human lineage
Jozef G�cz, Grant R. Sutherland (eds): Nucleotide and protein expansions and human disease. Karger, 2003, ISBN 3-8055-7621-8, 298 pp, hardcover, 95.50 Euros
Telomerase RNA deficiency in peripheral blood mononuclear cells in X-linked dyskeratosis congenita
Insights into the western Bantu dispersal: mtDNA lineage analysis in Angola
Landmarks in medical genetics: classic papers with commentaries. Peter S. Harper (ed), Oxford University Press, New York, 2004, ISBN 0-19-515930-6, 336 pages, hardcover, $89.50
A longitudinal study of X-inactivation ratio in human females
Low prevalence of MYOC mutations in UK primary open-angle glaucoma patients limits the utility of genetic testing
Functional analysis of two-amino acid substitutions in gp91phox in a patient with X-linked flavocytochrome b558-positive chronic granulomatous disease by means of transgenic PLB-985 cells
First case of aplastic anemia in a Japanese child with a homozygous missense mutation in the NBS1 gene (I171V) associated with genomic instability
Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload
Functional disomy resulting from duplications of distal Xq in four unrelated patients
Y chromosomal haplogroup J as a signature of the post-neolithic colonization of Europe
Role of an intronic polymorphism in the PDCD1 gene with the risk of sporadic systemic lupus erythematosus and the occurrence of antiphospholipid antibodies
Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2
Gender- and age-specific contributions of additional DNA sequence variation in the 5? regulatory region of the APOE gene to prediction of measures of lipid metabolism
Mutations
Inheritance mode of multiple sclerosis: the effect of HLA class II alleles is stronger than additive
Association between evolutionary history of angiotensinogen haplotypes and plasma levels
Variations in the C3, C3a receptor, and C5 genes affect susceptibility to bronchial asthma
The origin and spread of the HFE-C282Y haemochromatosis mutation
Genomic rearrangements at the IGHMBP2 gene locus in two patients with SMARD1
Concurrent analysis of loss of heterozygosity (LOH) and copy number abnormality (CNA) for oral premalignancy progression using the Affymetrix 10K SNP mapping array
CHX10 mutations cause non-syndromic microphthalmia/anophthalmia in Arab and Jewish kindreds Arab and Jewish kindreds
E.A. Carlson (ed) Mendel?s Legacy: the origin of classical genetics (2004)
Altered gating properties of functional Cx26 mutants associated with recessive non-syndromic hearing loss
A novel splice acceptor mutation in the DSPP gene causing dentinogenesis imperfecta type II
Identification of a novel type 1 diabetes susceptibility gene, T-bet
Paternal origin of FGFR3 mutations in Muenke-type craniosynostosis
Mutation analysis of subjects with 46, XX sex reversal and 46, XY gonadal dysgenesis does not support the involvement of SOX3 in testis determination
B. Wissinger, S. Kohl, U. Langenbeck (eds): Developments in ophthalmology vol 37: Genetics in ophthalmology
Max Perutz (ed) I wish I?d make you angry earlier. Expanded edition (2003)
Thomas von Zglinicki (ed) Aging at the molecular level (2003)
Qualitative and quantitative analysis of the effect of splicing mutations in propionic acidemia underlying non-severe phenotypes
Directional migration in the Hindu castes: inferences from mitochondrial, autosomal and Y-chromosomal data
Mono-nucleotide repeats (MNRs): a neglected polymorphism for generating high density genetic maps in silico
Chromosome 17p12-q11 harbors susceptibility loci for systemic lupus erythematosus
A resistin gene polymorphism is associated with body mass index in women
Nemaline myopathy in the Ashkenazi Jewish population is caused by a deletion in the nebulin gene Ashkenazi Jewish population
Alan E. Guttmacher, Francis S. Collins, Jeffrey M. Drazen (eds): Genomic medicine: articles from the New England Journal of Medicine
Human Gene Mutations
Identification and molecular modelling of a mutation in the motor head domain of myosin VIIA in a family with autosomal dominant hearing impairment (DFNA11)
Novel double-deletion mutations of the OFD1 gene creating multiple novel transcripts
Does haplotype diversity predict power for association mapping of disease susceptibility?
Lexikon der Syndrome und Fehlbildungen. Ursachen, Genetik, Risiken (2003)
A giant novel gene undergoing extensive alternative splicing is severed by a Cornelia de Lange-associated translocation breakpoint at 3q26.3
Increased amount of the angiotensin-converting enzyme (ACE) mRNA originating from the ACE allele with deletion
Supernumerary tricentric derivative chromosome 15 in two boys with intractable epilepsy: another mechanism for partial hexasomy
Human evolutionary genetics: origins, peoples, and disease (2004)
Mutations in the gene for the E1? subunit: a novel cause of pyruvate dehydrogenase deficiency
Myotonic dystrophy: present management, future therapy (2004)
Refinement of the 6p21.3 quantitative trait locus influencing dyslexia: linkage and association analyses
Somatic mutations of CASP3 gene in human cancers
Segmental duplication associated with the human-specific inversion of chromosome�18: a further example of the impact of segmental duplications on karyotype and genome evolution in primates
Lipoprotein lipase gene is in linkage with blood pressure phenotypes in Chinese pedigrees Chinese
An intragenic deletion/inversion event in the DMD gene determines a novel exon creation and results in a BMD phenotype
Ancestral proportions and their association with skin pigmentation and bone mineral density in Puerto Rican women from New York city
The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster
Mitochondrial DNA polymorphisms as risk factors for Parkinson?s disease and Parkinson?s disease dementia
Parents of children with autosomal recessive diseases are not always carriers of the respective mutant alleles
Mutations
A new locus for autosomal dominant Charcot-Marie-Tooth disease type�2 (CMT2L) maps to chromosome 12q24
Fine mapping of the Schnyder?s crystalline corneal dystrophy locus
Fine mapping a gene for pediatric gastroesophageal reflux on human chromosome 13q14
Novel microsatellite markers and single nucleotide polymorphisms refine the tylosis with oesophageal cancer ( TOC ) minimal region on 17q25 to 42.5�kb: sequencing does not identify the causative gene
SNURF-SNRPN and UBE3A transcript levels in patients with Angelman syndrome
Variants of CYP46A1 may interact with age and APOE to influence CSF A�42 levels in Alzheimer?s disease
The Genetic Basis of Common Diseases, 2nd Edition
Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis
Evidence for non-homologous end joining and non-allelic homologous recombination in atypical NF1 microdeletions
Small marker chromosomes in two patients with segmental aneusomy for proximal 17p
SNTG1, the gene encoding ?1-syntrophin: a candidate gene for idiopathic scoliosis
The origin of the isolated population of the Faroe Islands investigated using Y chromosomal markers
Eric Lander, David Page, Richard Lifton (eds): Annual review of genomics and human genetics (volume 4)
Regulation of the MID1 protein function is fine-tuned by a complex pattern of alternative splicing
Investigation of the Greek ancestry of populations from northern Pakistan
Clinical, histopathologic, and genetic investigation in two large families with dentinogenesis imperfecta type�II
A study of the distributional characteristics of FMR1 transcript levels in 238 individuals
Detection of DNA copy number abnormality by microarray expression analysis
Heart morphogenesis is not affected by overexpression of the Sh3bgr gene mapping to the Down syndrome heart critical region
New clues on the origin of the Friedreich ataxia expanded alleles from the analysis of new polymorphisms closely linked to the mutation
Encyclopedia of the human genome
New genomic region for Wegener?s granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes
Common variants of ACE contribute to variable age-at-onset of Alzheimer’s disease
Chasing genes in Alzheimer?s and Parkinson?s disease
A novel I247T missense mutation in the haptoglobin�2 �-chain decreases the expression of the protein and is associated with ahaptoglobinemia
Fine mapping of the 2p11 dyslexia locus and exclusion of TACR1 as a candidate gene
Quasi-linkage: a confounding factor in linkage analysis of complex diseases?
Delineation of complex chromosomal rearrangements: evidence for increased complexity
Association between IFNA genotype and the risk of sarcoidosis
Microarray Gene Expression Data Analysis: A Beginners Guide
Genetics of Movement Disorders
The thymidylate synthase tandem repeat polymorphism is not associated with homocysteine concentrations in healthy young subjects
The impact of factor XIIIa V34L polymorphism on plasma factor XIII activity in the Chinese and Asian Indians from Singapore Chinese; Asian Indians
Inherited variants in MYH are unlikely to contribute to the risk of lung carcinoma
Molecular and evolutionary analysis of the growth-controlling region on the human Y chromosome
Rowena Spencer (Editor) Conjoined twins. Developmental malformations and clinical implications
Identification of two AGTR2 mutations in male patients with non-syndromic mental retardation
Mutations
David Bainbridge (Editor), The X in sex: how the X chromosome controls our lives
Translocation breakpoint mapping and sequence analysis in three monosomy 1p36 subjects with der(1)t(1;1)(p36;q44) suggest mechanisms for telomere capture in stabilizing de novo terminal rearrangements
A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma
A comparison of the mutation spectra of Menkes disease and Wilson disease
Hugh Markus (Editor) Report on stroke genetics
Excavating Y-chromosome haplotype strata in Anatolia
A deletion mutation in the ?A1/A3 crystallin gene (CRYBA1/A3) is associated with autosomal dominant congenital nuclear cataract in a Chinese family
R. Horowoski, Y. Mizuno, C.W. Olanow, W.H. Poewe, P. Riederer, J.A. Stoessl, M.B.H. Youdim (Editors) Advances in research on neurodegeneration (volume 10)
The assertion that a G21V mutation in AGTR2 causes mental retardation is not supported by other studies
AGTR2 mutation and mental retardation: a reply
Mutations
David Reiss, Jenae M. Neiderhiser, E. Mavis Hetherington, Robert Plomin (Editors): The relationship code: deciphering genetic and social influences on adolescent development
Common variants within the interleukin 4 receptor ? gene (IL4R) are associated with susceptibility to osteoarthritis
Haplotype mapping of the bronchiolitis susceptibility locus near IL8
Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria
Update on the genetics of migraine
Mexican American ancestry-informative markers: examination of population structure and marker characteristics in European Americans, Mexican Americans, Amerindians and Asians European Americans
Members of the CDY family have different expression patterns: CDY1 transcripts have the best correlation with complete spermatogenesis
Novel SBDS mutations caused by gene conversion in Japanese patients with Shwachman-Diamond syndrome
Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase
Public Health Genetics
Bronya J.B. Keats, Arthur N. Popper, Richard R. Fay (Editors) Springer handbook of auditory research: genetics and auditory disorders
Apolipoprotein B-100 Xba I gene polymorphism in gallbladder cancer
Genetics and genomics of neurobehavioral disorders
G. Bates, P. Harper, L. Jones (eds): Huntington?s Disease, Third Edition
Acknowledgement to referees 2003
Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm
Analysis of heat-shock protein�70 gene polymorphisms and the risk of Parkinson?s disease
Small deletions disturb desmin architecture leading to breakdown of muscle cells and development of skeletal or cardioskeletal myopathy
Single cell co-amplification of polymorphic markers for the indirect preimplantation genetic diagnosis of hemophilia�A, X-linked adrenoleukodystrophy, X-linked hydrocephalus and incontinentia pigmenti
A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia
U. Eiholzer, D. L?Allemand, WB. Zipf (eds): Prader-Willi syndrome as a model for obesity
Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria
A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree
Origin and spread of the 1278insTATC mutation causing Tay-Sachs disease in Ashkenazi Jews: genetic drift as a robust and parsimonious hypothesis
Contrasting patterns of Y chromosome variation in Ashkenazi Jewish and host non-Jewish European populations host non-Jewish European populations
Genetics of parkin-linked disease
Patterns of linkage disequilibrium in the MHC region on human chromosome 6p
TP53 haplotype-based analysis and incidence of post-angioplasty restenosis