Human Genetics - 1984

286 articles | Last updated: 2025-12-03 14:12:56
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Increased sister chromatid exchanges in human cell lines characterized by monosomy X or structural abnormalities of the X chromosome
The frequency of 47,+21, 47,+18, and 47,+13 at the uppermost extremes of maternal ages: results on 56,094 fetuses studied prenatally and comparisons with data on livebirths
Human genes for glutathione S-transferases
Studies on chiasma frequency and distribution in two fertile men carrying reciprocal translocations; one with a t(9;10) karyotype and one with a t(Y;10) karyotype
The gene in search of an identity
Separation of retinoblastoma and esterase D loci in a patient with sporadic retinoblastoma and del(13)(q14.1q22.3)
Origin of extra chromosome in Patau syndrome
Disturbances in collagen synthesis in trisomic cells from spontaneously aborted embryos
Life span elongation of Werner's syndrome fibroblasts by co-culture with origin-defective SV-40 DNA transformed cells
Fanconi anaemia cells are not uniformly deficient in unhooking of DNA interstrand crosslinks, induced by mitomycin C or 8-methoxypsoralen plus UVA
Relationship of the variability of the heterochromatic regions of chromosomes 1, 9, 16, and Y to some anthropometric characteristics in children with embryopathies of unknown etiology and in children
?-Globin gene deletion causes ?-thalassemia syndromes in two German families
A new ?2HS-glycoprotein allele (AHS * 5 ?) in two Japanese families
Partial trisomy 18 due to a maternal translocation t(9;18)
Prenatal diagnosis by trophoblast sampling
An aetiological study of 290 XXY males, with special reference to the role of paternal age
Atypical metachromatic leukodystrophy?
The beta chorionic gonadotropin-beta luteinizing gene cluster maps to human chromosome 19
Prenatal identification of a deleted Y chromosome by cytogenetics and a Y-specific repetitive DNA probe
Is a gene for microcephaly located on chromosome 1?
Diagnostic insonation of extra utero human placentas: No effect of lymphocytic sister chromatid exchange
A study of lactose absorption capacity in twins
Regional mapping of the human gene for lysosomal ?-glucosidase by in situ hybridization
The isolation of a genomic clone containing the apolipoprotein CII gene and the detection of linkage disequilibrium between two common DNA polymorphisms around the gene
?-Thalassemia among sickle cell anemia patients in various African populations
Mitochondrial DNA polymorphism in Japanese Japanese
Conservation of the human COL1A1-TK-GAA synteny and homoeologous assignment in the African green monkey and the baboon (Cercopithecoidae)
Yqs in an American family of Scottish descent Scottish descent
Pyruvate dehydrogenase activity is not deficient in the brain of three autopsied cases with Leigh disease (subacute necrotizing encephalomyelopathy, SNE)
Complementation analysis in lymphoid cells from five patients with different forms of maple syrup urine disease
Reproductive outcomes of paracentric inversion carriers: Report of a liveborn dicentric recombinant and literature review
Coagulation factor XIII: A useful polymorphic genetic marker
DNA polymerase ? inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes
A nonparametric and a parametric version of a test for the detection of the presence of a major gene applicable on data for the complete nuclear family
Familial apolipoprotein CII deficiency: A preliminary analysis of the gene defect in two independent families
Meiotic studies and synaptonemal complex analysis in two infertile males with a 13/14 balanced translocation
Population and formal genetics of the human C81(?-?) polymorphism
Estimating the Recombination frequency for the PTC-Kell linkage
A de novo case of trisomy 10p: Gene dosage studies of hexokinase, inorganic pyrophosphatase and adenosine kinase
New chromosomal syndrome: Miller-Dieker syndrome and monosomy 17p13
PI (?1) polymorphism in the Japanese: Confirmation of PI*M4 and description of new PI variants
Comparison of expression of the fragile site at Xq27 in T and B lymphocytes
The Cd technique identifies a specific structure related to centromeric function
A leftward deletional ?+ thalassemia found in East Sicily in conjunction with heterozygous ?-thalassemia
Trisomy 11p15 and Beckwith-Wiedemann syndrome. A report of two cases
Identical twins with deletion 16q syndrome: Evidence that 16q12.2-q13 is the critical band region
Y chromosome R-bands
Prenatal diagnosis of Sanfilippo disease type B
Determination of aldehyde dehydrogenase phenotypes using hair roots: Re-examination
Contribution of reciprocal translocations to an understanding of chromosome displacement: Inferences for studies of spatial order at metaphase
Synaptonemal complex studies in a mosaic 46,XY/47,XXY male
On the origin of chromosomal aberrations in human peripheral lymphocytes in vitro
Heterozygous female carriers of the marker-X-chromosome: IQ estimation and replication status of fra(X)(q)
The use of cloned Y chromosome-specific DNA probes for fetal sex determination in first trimester prenatal diagnosis
Red cell glutathione peroxidase (GPX1) variation in Afro-Jamaican, Asiatic Indian, and Dutch populations Afro-Jamaican, Asiatic Indian, Dutch
Transferrin subtypes and variants in Germany; Further evidence for a Tf null allele
Mean corpuscular hemoglobin is increased in Martin-Bell syndrome
A comparative study on steroid sulfatase and arylsulfatase C in fibroblast clones from 45,X/47,XXX and 69,XXY
HLA antigens, glyoxalase I, and esterase D in Hong Kong Chinese Hong Kong Chinese
The inducible fragile site on chromosome 3
Hae III restriction of DNA from three cases with nonfluorescent Y chromosomes (45XO/46XYnf)
High-resolution studies in patients with aniridia-Wilms tumor association, Wilms tumor or related congenital abnormalities
Human chromosome hot points
Duchenne muscular dystrophy
5-Azacytidine-induced undercondensations in human chromosomes
Considerations on the mechanism of differential Giemsa staining of BrdU-substituted chromosomes
A ?new? low incidence red cell antigen, NFLD
Anthropometric definitions of dysmorphic facial signs
Unusual scarcity of restriction site polymorphism in the human thyroglobulin gene. A linkage study suggesting autosomal dominance of a defective thyroglobulin allele
Erythrocyte phosphoglucomutase: A family study of a PGM1 deficient allele
The locus for apolipoprotein CII is closely linked to the apolipoprotein E locus on chromosome 19 in man
Cytochemical and biochemical studies on neutrophil alkaline phosphatase in parents of trisomy 21 children
Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes
Prevalence of partial deficiency of red cell triosephosphate isomerase in Germany ? a study of 3000 people
Genetic polymorphism of G6PD in a Bulgarian population Bulgarian population
Ecogenetic studies in Atacame�o Indians
Excess paternal meiotic errors in Turner syndrome: natural result of ascertainment bias
A case of achondrogenesis type I
The fragile site on chromosome 3
Esophageal atresia, coloboma, and clubfoot in two unrelated infants
Announcements
Announcements
Announcements
Further studies on compartmentalisation of DNA-topoisomerase I in Fanconi anemia tissue
Localisation of genetic markers and orientation of the linkage group on chromosome 19
Nonrandom distribution of methotrexate-induced aberrations on human chromosomes. Detection of further folic acid sensitive fragile sites
Spindle microtubular dysfunction in mothers of Down syndrome children
Intercellular NOR-AG variability in man
Prenatal detection of an unstable ring 21 chromosome
Population studies on human phosphoglucomutase-1 thermostability polymorphism
Aspects of sickle cell gene in Saudi Arabia?interaction with glucose-6-phosphate dehydrogenase deficiency
Homozygosity for fragile site at 17p12 in a 28-year-old healthy man
Verification of Lyon's hypothesis in fragile X carriers
Reply to Hecht and Hecht
Genetic aspects of hemifacial microsomia
Announcements
PI LBEI and PI JHOU: two new alpha-1-antitrypsin alleles
Isolation and subregional mapping of a human cDNA clone detecting a common RELP on chromosome 12
The gene for human fibroblast interferon (IFB) maps to 9p21
Pure monosomy and trisomy 2q24.2?q3105 due to an inv ins(7;2)(q21.2;q3105q24.2) segregating in four generations
Two new Bf S subtypes revealed by isoelectric focusing and immunofixation
Segregation of two independent chromosomal translocations in one family
Partial deficiency of hypoxanthine-guanine phosphoribosyltransferase with reduced affinity for PP-ribose-P in four related males with gout
Inherited XX sex reversal in the cocker spaniel dog
The phenotype in partial 13q trisomies, apropos of a familial (13;15)(q22;q26) translocation
Expression of an X-linked muscular dystrophy in a female due to translocation involving Xp21 and non-random inactivation of the normal X chromosome
A familial paracentric inversion: A short review of the current status
Unbalanced reciprocal translocations in cases of Prader-Willi syndrome
The locus for apolipoprotein E (apoE) is close to the Lutheran (Lu) blood group locus on chromosome 19
Harvey-ras allele deletion detected by in situ hybridization to Wilms' tumor chromosomes
Facioscapulohumeral muscular dystrophy concentrated in the village Çullar, Nevşhir, Turkey
Analysis of the DNA replication pattern of a translocation (tX/X, qter→p221::p223→qter) chromosome in leukocyte and fibroblast cultures
Interstitial deletion of the short arm of chromosome 17
Meiotic translocations in two sterile males
DNA restriction fragment length polymorphisms and heterozygosity in the human genome
Duchenne muscular dystrophy: Pathogenetic aspects and genetic prevention
Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: Verification by standard staining techniques, new densitometric methods, and somatic cell hybridization
Genetic polymorphism of complement C6 and haplotype analysis between C6 and C7 in a Japanese population Japanese population
Development and behavior of synaptonemal complexes in human spermatocytes by light and electron microscopy
The identification of a DNA polymorphism of the ? fibrinogen gene, and the regional assignment of the human fibrinogen genes to 4q26-qter
The positions of three restriction fragment length polymorphisms on chromosome 4 relative to known genetic markers
Apolipoprotein E phenotypes and hyperlipidemia
Characterization of the distribution of sister chromatid exchange frequencies: Implications for research design
Regional localization of the human genes for S-adenosylhomocysteine hydrolase (cen?q131) and adenosine deaminase (q131?qter) on chromosome 20
Genetic complementation in somatic cell hybrids of cerebroside sulfatase activator deficiency and metachromatic leukodystrophy fibroblasts
Localization of the polymorphic human calcitonin gene on chromosome 11
Chromosome 15 anomalies and the Prader-Willi syndrome: Cytogenetic analysis
Banding of unfixed mitotic chromosomes in suspension after release from human lymphocytes and fibroblasts
Four cases of partial trisomy 4p by preferential segregation in a familial 4p/17q balanced translocation
Clonal inheritance versus variability of rRNA gene activity in human fibroblasts
Effect of caffeine in G2 on X-ray-induced chromosomal aberrations and mitotic inhibition in ataxia telangiectasia fibroblast and lymphoblastoid cells
Autosomal fragile sites not a current indication for prenatal diagnosis
Compound heterozygotes in hyperphenylalaninemia
A gene regulating the time dependence of ?-l-fucosidase concentration is closely linked with the structural gene in man
Further study on a BF silent allele
Chromosome 13 restriction fragment length polymorphisms
First-trimester diagnosis on chorionic villi obtained by direct vision technique
Ethnic distribution of phenylketonuria in the north German population north German population
Editorial help
X-linked agammaglobulinemia and the red blood cell determinants Xg and 12E7 are not closely linked
Fetal mortality at the time of chorionic villi sampling
Hyalinosis cutis et mucosae in siblings
Confirmation of the assignment of the gene coding for the BA-2 antigen to human chromosome 12
Announcements
Announcements
Pericentric inversions
HLA as a marker of the hemochromatosis gene in Sweden
A unique electrophoretic slow-moving glucose 6-phosphate dehydrogenase variant (G6PD Asahikawa) with a markedly acidic pH optimum
The mode of inheritance of psoriasis: Evidence for a major gene as well as a multifactorial component and its implication for genetic counselling
The phenotypic effects of small, distal Xq deletions
Announcement
Localisation of the Becker muscular dystrophy gene on the short arm of the X chromosome by linkage to cloned DNA sequences
Exclusion of chromosomal mosaicism in prenatal diagnosis
Osteogenesis imperfecta: a heterogeneous morphologic phenotype in cultured dermal fibroblasts
DNA replication and inactivation patterns in structural abnormality of sex chromosomes
Polymorphisms of human albumin gene after DNA restriction by Hae III endonuclease
Heterozygous carriers for Bloom syndrome exhibit a spontaneously increased micronucleus formation in cultured fibroblasts
Statistical evaluation of sister chromatid exchanges
A new ?2HS-glycoprotein typing by isoelectric focusing
Satellited Y chromosomes: Structure, origin, and clinical significance
Persistence of chromosome rearrangements in peripheral lymphocytes from patients treated with melphalan for ovarian carcinoma
Fragile (X) expression: Relationship to the cell cycle
Y-Dependent polypeptides identified by two-dimensional gel electrophoresis of monozygotic X0 and XY fibroblasts
A list of cloned human DNA sequences-Supplement
Ring chromosome 21 in a healthy woman with three spontaneous abortions
Use of a chromosome 21 cloned DNA probe for the analysis of non-disjunction in Down syndrome
G6PD Cagliari: A new low activity glucose 6-phosphate dehydrogenase variant characterized by enhanced intracellular lability
A new form of hypertrichosis inherited as an X-linked dominant trait
X-inactivation patterns in lymphocytes and skin fibroblasts of three cases of X-autosome translocations with abnormal phenotypes
Cytogenetic studies in spontaneous abortuses
Linkage between late onset, dominant spinocerebellar ataxia and HLA
Genetic polymorphism of mitochondrial glutamate-oxaloacetate transaminase in Japanese
Premature centromere splitting in a presumptive mild form of Roberts syndrome
Fragile X ?homozygosity? due to somatic crossing-over?
Announcements
Announcements
Cystic kidneys
Distal duplication 14q: Report of three cases and further delineation of the syndrome
Genetic linkage between erythrokeratodermia variabilis and Rh locus
Characterization of normal and mutant adenosine deaminase messenger RNAs by translation and hybridization to a cDNA probe
The association of the nucleolus and the short arm of acrocentric chromosomes with the XY pair in human spermatocytes: Its possible role in facilitating sex-chromosome acrocentric translocations
The two apolipoprotein loci apoA-I and apoA-IV are closely linked in man
Folic acid and chromosome breakage. II. A methionine effect similar to that in fragile X expression
Gene frequencies of S-adenosylhomocysteine hydrolase (SAHH) in a Japanese population Japanese population
Trisomy 14 by paternal origin
Apolipoprotein E phenotypes in patients with myocardial infarction
Reactivity pattern of 15 HLA-Dw1 homozygous typing cells in primary mixed lymphocyte culture
Familial thrombocytopenia associated with platelet autoantibodies and chromosome breakage
Properties of ?-l-iduronidase in cultured skin fibroblasts from ?-l-iduronidase-deficient patients
A simple method for high resolution banding of chromosomes in amniotic fluid cells
Transferase-deficiency galactosemia: Immunochemical studies of the Duarte and Los Angeles variants
Old and new genetics help ordering loci at the telomere of the human X-chromosome long arm
Hemoglobins S and C in Upper Volta
?-Globin gene deletions associated with ?Aand ?G Philadelphiagenes in an Algerian family that includes two Hb G homozygotes
Meiotic studies in two infertile males with autosomal translocations
Trisomy 16q13?qter in a infant from a t (11;16)(q25;q13) translocation-carrier father
Announcement
Modification in publication of articles dealing with genetic polymorphisms
Genetic changes in mammalian cells reminiscent of an SOS response
Three new phenotypes of human red cell acid phosphatase: ACP1FA, ACP1GA, and ACP1GB
A re-examination of the case for homology between the X and Y chromosomes of mouse and man
Telomeric association of chromosomes in B-cell lymphoid leukemia
On the development of a standard two-dimensional polypeptide map of the human X chromosome
The gene for coagulation factor XIII a subunit (F13A) is distal to HLA on chromosome 6
A new X-linked dysplasia gigantism syndrome: Identical with the Simpson dysplasia syndrome?
Transmission of the marker X syndrome trait by unaffected males: Conclusions from studies of large families
Restriction fragment length polymorphisms at the human parathyroid hormone gene locus
Familial benign hypercalcaemia (FBH; McK. No. 14598, 1983): Linkage studies in a large Dutch family
Del11p13/nephroblastoma without aniridia
X-Y translocation. A case report
X-linked Duchenne muscular dystrophy in an unusual family with manifesting carriers
Familial DiGeorge syndrome and associated partial monosomy of chromosome 22
Cytogenetic studies of familial Prader-Willi syndrome
Discrete subaortic stenosis as part of a short stature syndrome
Study on established lymphoid cells in maple syrup urine disease. Correlation with clinical heterogeneity
Human C4 polymorphism: Pedigree analysis of qualitative, quantiative, and functional parameters as a basis for phenotype interpretations
The use of distamycin A in human lymphocyte cultures
Detailed cell cycle analysis in human lymphocytes; Application to ?-irradiated cells
Inactivation pattern of the fragile X in heterozygous carriers
Gd (+) Laguna, a new rare glucose-6-phosphate dehydrogenase variant from Brazil
Compoond heterozygotes in hyperphenylalaninaemia
Letters to the editors
Autosomal lesions versus fragile sites
X long-arm deletions. A review of non-mosaic cases studied with banding techniques
Genetic mapping of the structural gene for antithrombin III to human chromosome 1
Prevalence of primary adult lactose malabsorption in three populations of northern China
No marker (X) syndrome in autistic children
Maternal ageing and aneuploid embryos?Evidence from the mouse that biological and not chronological age is the important influence
Bleomycin-induced chromosomal aberrations and sister chromatid exchanges in Down lymphocyte cultures
Isoelectric focusing studies of human red cell esterase D: Evidence for polymorphic occurrence of a new allele EsD 7 in Japanese Japanese
Epidemiology of neural tube defects in Germany
Regional mapping of liver type 6 phosphofructokinase isoenzyme on chromosome 21
Electrophoretic variants of blood proteins in Japanese
Announcement
Chromosome abnormalities and season of birth
Prenatal diagnosis of cystic fibrosis by assay of amniotic fluid microvillar enzymes
Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes
Identification of cells from fetal bladder epithelium in human amniotic fluid
Detection of H-Y in the enzyme-linked immunosorbent assay
Assignment of the gene for cystathionine ?-synthase to human chromosome 21 in somatic cell hybrids
Reply to the comments by Mayerov�, M�ller, Wiberg, Wolf, and Fraccaro Hum Genet 66:110?112
Human oncogenes
Chromosome studies in 496 infertile males with a sperm count below 10 million/ml
Familial inv(1)(p3500q21.3) associated with azoospermia
A decreasing tendency for cytogenetic abnormality in peripheral lymphocytes of retinoblastoma patients with 13q14 deletion mosaicism
The use of fructose 1-phosphate to detect Hunter heterozygotes in fibroblast cultures from high-risk carriers
Cytogenetic investigations in mentally retarded and normal males from 14 families with the fragile site at Xq28
Population genetics of the vitamin D binding protein (GC) subtypes in the Asian-Pacific area: Description of new alleles at the GC locus
Heterochromatin and nucleolus organizer regions in cells of patients with malignant and premalignant lymphatic diseases
Diagnosis of infantile and juvenile forms of GM2 gangliosidosis variant 0. residual activities toward natural and different synthetic substrates
Gaucher disease: The effects of phosphatidylserine on glucocerebrosidase from normal and Gaucher fibroblasts
C3 polymorphism, HLA and chronic renal failure in Spaniards
Techniques for estimating genetic admixture and applications to the problem of the origin of the Icelanders and the Ashkenazi Jews
Cytogenetic survey in couples with recurrent fetal wastage
Steroid sulphatase in man: A non inactivated X-locus with partial gene dosage compensation
Genetics of urinary pepsinogen: A new hypothesis
The current state of research with peripheral tissues in Huntington disease
Karyotyping and identification of human chromosome polymorphisms by single fluorochrome flow cytometry
Arylsulfatase A in pseudodeficiency
Non-random in vitro 7;14 translocations detected in a routine cytogenetic series. 12 Examples and their possible significance
Assignment of the gene for uroporphyrinogen decarboxylase to human chromosome 1 by somatic cell hybridization and specific enzyme immunoassay
Sequence of centromere separation another mechanism for the origin of nondisjunction
Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis:
Complete pachytene chromomere karyotypes of human spermatocyte bivalents
A sensitive and dependable assay for distinguishing hamster and human X-linked steroid sulfatase activity in somatic cell hybrids
Variability in serologically detected male antigen titer and some resulting problems: A critical review
Comments on the paper by M. T. Zenzes and T. E. Reed hum genet 66:103?109 (1984)
Heterocellular hereditary persistence of fetal hemoglobin (HPFH). Molecular mechanisms of abnormal ?-gene expression in association with ? thalassemia and linkage relationship with the ?-globin gene c
A new glucose-6-phosphate dehydrogenase variant (G-6-PD Kalyan) found in a Koli family
Meiotic configurations in female trisomy 21 foetuses
Regional mapping of catalase and Wilms tumor?aniridia, genitourinary abnormalities, and mental retardation triad loci to the chromosome segment 11p1305?p1306
Assignment of human phosphoribosylglycinamide synthetase locus to region 21q221
Chromosomal abnormalities in human sperm: Comparisons among four healthy men
Localization of a gene which complements branched-chain amino acid transaminase deficiency to the short arm of human chromosome 12
Restriction site polymorphism in the phosphoglycerate kinase gene on the X chromosome
Synchronization of human leukemic cells: Relevance for high-resolution chromosome banding
Estimation of aneuploidy levels in human spermatozoa using chromosome specific probes and in situ hybridisation
Familial congenital esophageal atresia
Genetic polymorphism of the seventh component of complement in a Japanese population Japanese population
Smaller autosomal C band sizes in blacks than in caucasoids blacks; caucasoids
Differential enzyme activities in human esterase D phenotypes
Regional mapping of clotting factors VII and X to 13q34. Expression of factor VII through chromosome 8
Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis:
Diagnostic application of first trimester trophoblast sampling in 100 pregnancies
Gd(-) Gifu and Gd(-) Fukuoka. Two new variants of glucose-6-phosphate dehydrogenase found in Japan
Siblings with renal tubular acidosis and nerve deafness. The first family in Japan