Genetic Epidemiology - 2022

48 articles | Last updated: 2025-12-03 14:12:56
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T A T A T A T A
Improved two‐step testing of genome‐wide gene–environment interactions
Efficient identification of trait‐associated loss‐of‐function variants in the UK Biobank cohort by exome‐sequencing based genotype imputation UKB homogeneous European participants
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons
Adaptive Bayesian variable clustering via structural learning of breast cancer data
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Multivariate analysis of a missense variant in <i>CREBRF</i> reveals associations with measures of adiposity in people of Polynesian ancestries
Sparse prediction informed by genetic annotations using the logit normal prior for Bayesian regression tree ensembles
Statistical methods for <i>cis</i>‐Mendelian randomization with two‐sample summary‐level data
An empirical Bayes approach to improving population‐specific genetic association estimation by leveraging cross‐population data non‐European ancestry; European ancestry population; trans‐ancestry GWAS
Mediation analysis of multiple mediators with incomplete omics data
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Abstracts
An exploration of linkage fine‐mapping on sequences from case‐control studies
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens
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Including diverse and admixed populations in genetic epidemiology research
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference
Sparse group variable selection for gene–environment interactions in the longitudinal study
Control for population stratification in genetic association studies based on GWAS summary statistics
Statistical power of transcriptome‐wide association studies
A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states
Novel HLA associations with outcomes of <i>Mycobacterium tuberculosis</i> exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection individuals of African ancestry
Post hoc power is not informative
Clarifying the causes of consistent and inconsistent findings in genetics
Analysis of parent‐of‐origin effects for secondary phenotypes using case–control mother–child pair data
Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization
Adjusting for collider bias in genetic association studies using instrumental variable methods
Statistical methods for Mendelian models with multiple genes and cancers
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Selection bias when inferring the effect direction in Mendelian randomization
Gene‐environment interaction in type 2 diabetes in Korean cohorts: Interaction of a type 2 diabetes polygenic risk score with triglyceride and cholesterol on fasting glucose levels Korean cohorts; multiethnic data
Benchmarking statistical methods for analyzing parent–child dyads in genetic association studies multiethnic mother–child pairs
Gene‐level association analysis of ordinal traits with functional ordinal logistic regressions
Exploring polygenic‐environment and residual‐environment interactions for depressive symptoms within the UK Biobank
RAVAQ: An integrative pipeline from quality control to region‐based rare variant association analysis
Secondary analyses for genome‐wide association studies using expression quantitative trait loci
A two‐sample robust Bayesian Mendelian Randomization method accounting for linkage disequilibrium and idiosyncratic pleiotropy with applications to the COVID‐19 outcomes
Genome‐wide association study of multiethnic nonsyndromic orofacial cleft families identifies novel loci specific to family and phenotypic subtypes
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The influence of unmeasured confounding on the MR Steiger approach
Interaction between genetics and smoking in determining risk of coronary artery diseases participants of European ancestry
Integrating external controls in case–control studies improves power for rare‐variant tests
Collider bias from selecting disease samples distorts causal inferences
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Genome‐wide association studies of 27 accelerometry‐derived physical activity measurements identified novel loci and genetic mechanisms
Genome‐wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores