| A novel association of rs13334070 in the RPGRIP1L gene with adiposity factors discovered by joint linkage and linkage disequilibrium analysis in Iranian pedigrees: Tehran Cardiometabolic Genetic Study |
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| System for Quality‐Assured Data Analysis: Flexible, reproducible scientific workflows |
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| Relative impact of indels versus SNPs on complex disease |
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SardiNIA study; isolated valley in Sardinia |
| Prediction of treatment response in rheumatoid arthritis patients using genome‐wide SNP data |
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| Issue Information |
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| Linear mixed models for association analysis of quantitative traits with next‐generation sequencing data |
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| Loss of function, missense, and intronic variants in <i>NOTCH1</i> confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts |
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European‐ancestry individuals; non‐European and mixed ancestry |
| Beyond the traditional simulation design for evaluating type 1 error control: From the “theoretical” null to “empirical” null |
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| Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals |
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| Estimating cross‐population genetic correlations of causal effect sizes |
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Europeans; East Asians; South Asians; continental populations |
| Using Bayes model averaging to leverage both gene main effects and <i>G</i> × <i>E</i> interactions to identify genomic regions in genome‐wide association studies |
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| An optimal kernel‐based <i>U</i>‐statistic method for quantitative gene‐set association analysis |
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| Generalized multifactor dimensionality reduction approaches to identification of genetic interactions underlying ordinal traits |
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Multi‐Ethnic Study of Atherosclerosis |
| Generalizing polygenic risk scores from Europeans to Hispanics/Latinos |
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European ancestry (EA) |
| Variance components genetic association test for zero‐inflated count outcomes |
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| ComPaSS‐GWAS: A method to reduce type I error in genome‐wide association studies when replication data are not available |
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| Issue Information |
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| Overlapping clustering of gene expression data using penalized weighted normalized cut |
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| Bias in parameter estimates due to omitting gene–environment interaction terms in case‐control studies |
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| Multi‐SKAT: General framework to test for rare‐variant association with multiple phenotypes |
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| Fisher’s influence on me |
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| The 2018 Annual Meeting of the International Genetic Epidemiology Society |
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| The accuracy of LD Score regression as an estimator of confounding and genetic correlations in genome‐wide association studies |
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| Inferring disease risk genes from sequencing data in multiplex pedigrees through sharing of rare variants |
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| Partial likelihood ratio test for X‐chromosome association models |
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| Adjustment for covariates using summary statistics of genome‐wide association studies |
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| A small‐sample kernel association test for correlated data with application to microbiome association studies |
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| Genetic association analysis with pedigrees: Direct inference using the composite likelihood ratio |
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| Issue Information |
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| Genome‐wide interaction studies identify sex‐specific risk alleles for nonsyndromic orofacial clefts |
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| A linear mixed model framework for gene‐based gene–environment interaction tests in twin studies |
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| General retrospective mega‐analysis framework for rare variant association tests |
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| A robust method to estimate regional polygenic correlation under misspecified linkage disequilibrium structure |
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| The evidential statistical paradigm in genetics |
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| Erratum |
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| Bias in Mendelian randomization due to assortative mating |
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| Hierarchical modeling of melanocortin 1 receptor variants with skin cancer risk |
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lightly pigmented populations |
| Efficient computation of the joint probability of multiple inherited risk alleles from pedigree data |
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| FastSKAT: Sequence kernel association tests for very large sets of markers |
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| A subregion‐based burden test for simultaneous identification of susceptibility loci and subregions within |
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| Issue Information |
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| Gene–environment interactions in case–control studies with silent disease |
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| Statistics for X‐chromosome associations |
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| Analysis of pedigree data in populations with multiple ancestries: Strategies for dealing with admixture in Caribbean Hispanic families from the ADSP |
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Caribbean Hispanic; multiethnic; admixed; ancestry; ancestral origin |
| Issue Information |
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| Transcriptome‐wide association studies accounting for colocalization using Egger regression |
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| SimPEL: Simulation‐based power estimation for sequencing studies of low‐prevalence conditions |
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| A univariate perspective of multivariate genome‐wide association analysis |
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| Method to estimate the approximate samples size that yield a certain number of significant GWAS signals in polygenic traits |
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| Generalized Hotelling's test for paired compositional data with application to human microbiome studies |
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| Improved score statistics for meta‐analysis in single‐variant and gene‐level association studies |
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| Genome‐wide interaction with the insulin secretion locus <i>MTNR1B</i> reveals <i>CMIP</i> as a novel type 2 diabetes susceptibility gene in African Americans |
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in Europeans; African Americans; individuals of East Asian ancestry |
| Genetic associations with childhood brain growth, defined in two longitudinal cohorts |
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| A hierarchical clustering method for dimension reduction in joint analysis of multiple phenotypes |
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| A multiple mediator analysis approach to quantify the effects of the ADH1B and ALDH2 genes on hepatocellular carcinoma risk |
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| Testing cross‐phenotype effects of rare variants in longitudinal studies of complex traits |
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| POLARIS: Polygenic LD‐adjusted risk score approach for set‐based analysis of GWAS data |
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| Cover Image |
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| Issue Information |
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| Interaction of a genetic risk score with physical activity, physical inactivity, and body mass index in relation to venous thromboembolism risk |
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| Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents |
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✓ |
Mexican American |
| Powerful and robust cross‐phenotype association test for case‐parent trios |
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| Issue Information |
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| A meta‐analysis approach with filtering for identifying gene‐level gene–environment interactions |
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| An analytic approach for interpretable predictive models in high‐dimensional data in the presence of interactions with exposures |
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| A test for gene–environment interaction in the presence of measurement error in the environmental variable |
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| Integrating eQTL data with GWAS summary statistics in pathway‐based analysis with application to schizophrenia |
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| Whole genome association study of brain‐wide imaging phenotypes: A study of the ping cohort |
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| Issue Information |
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| Strategies for phasing and imputation in a population isolate |
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| Inference on phenotype‐specific effects of genes using multivariate kernel machine regression |
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