Genetic Epidemiology - 2017

76 articles | Last updated: 2025-12-03 14:12:56
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T A T A T A T A
Properties of global‐ and local‐ancestry adjustments in genetic association tests in admixed populations global ancestry, local ancestry, admixed populations, ancestral populations, ancestry-adjusted, ance
Kernel machine methods for integrative analysis of genome‐wide methylation and genotyping studies
On the substructure controls in rare variant analysis: Principal components or variance components?
Integrating genome‐wide association study summaries and element‐gene interaction datasets identified multiple associations between elements and complex diseases
A deeper look at two concepts of measuring gene–gene interactions: logistic regression and interaction information revisited
Estimating and testing direct genetic effects in directed acyclic graphs using estimating equations
Two‐phase designs for joint quantitative‐trait‐dependent and genotype‐dependent sampling in post‐GWAS regional sequencing
A robust and powerful two‐step testing procedure for local ancestry adjusted allelic association analysis in admixed populations African American ("African American participants"; "African Americans")
Methods for meta‐analysis of multiple traits using GWAS summary statistics
Multifactorial disease risk calculator: Risk prediction for multifactorial disease pedigrees
Gene‐based genetic association test with adaptive optimal weights
Predictive accuracy of combined genetic and environmental risk scores
Using imputed genotype data in the joint score tests for genetic association and gene–environment interactions in case‐control studies
A unified partial likelihood approach for X‐chromosome association on time‐to‐event outcomes
Estimating the number of potential family members eligible for <i>BRCA1</i> and <i>BRCA2</i> mutation testing in a “Traceback” approach
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Family‐based tests for associating haplotypes with general phenotype data
Identification of 16q21 as a modifier of nonsyndromic orofacial cleft phenotypes
An integrative approach to assess X‐chromosome inactivation using allele‐specific expression with applications to epithelial ovarian cancer
Multiethnic polygenic risk scores improve risk prediction in diverse populations European samples; European ancestry; European; Latino; Native American; South Asian; African
On meta‐ and mega‐analyses for gene–environment interactions
An ancestry‐based approach for detecting interactions the fraction of European/African ancestry in African Americans; African American and Latino admixed individuals
Integrative sparse principal component analysis of gene expression data
Testing for the indirect effect under the null for genome‐wide mediation analyses
Rare‐variant association tests in longitudinal studies, with an application to the Multi‐Ethnic Study of Atherosclerosis (MESA) Multi‐Ethnic
On the testing of Hardy‐Weinberg proportions and equality of allele frequencies in males and females at biallelic genetic markers
Impact of sample collection participation on the validity of estimated measures of association in the National Birth Defects Prevention Study when assessing gene‐environment interactions
Corrigendum
Estimation of a significance threshold for epigenome‐wide association studies
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Phenotype validation in electronic health records based genetic association studies
Mendelian randomization with fine‐mapped genetic data: Choosing from large numbers of correlated instrumental variables
Evolutionarily derived networks to inform disease pathways
Analysis of cancer gene expression data with an assisted robust marker identification approach
The more you test, the more you find: The smallest <i>P</i>‐values become increasingly enriched with real findings as more tests are conducted
Iterative hard thresholding for model selection in genome‐wide association studies
A multivariate distance‐based analytic framework for microbial interdependence association test in longitudinal study
Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels
A functional U‐statistic method for association analysis of sequencing data
The 2017 Annual Meeting of the International Genetic Epidemiology Society
Issue Information
An efficient study design to test parent‐of‐origin effects in family trios
Adaptive testing for association between two random vectors in moderate to high dimensions
A comparison of methods for inferring causal relationships between genotype and phenotype using additional biological measurements
Joint genotype‐ and ancestry‐based genome‐wide association studies in admixed populations
Improving power for rare‐variant tests by integrating external controls
Accommodating missingness in environmental measurements in gene‐environment interaction analysis
Integrative eQTL analysis of tumor and host omics data in individuals with bladder cancer
A genetic stochastic process model for genome‐wide joint analysis of biomarker dynamics and disease susceptibility with longitudinal data
Detecting genetic association through shortest paths in a bidirected graph
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Integrative gene set enrichment analysis utilizing isoform‐specific expression
Region‐based association tests for sequencing data on survival traits
PhredEM: a phred-score-informed genotype-calling approach for next-generation sequencing studies
Polygenic scores via penalized regression on summary statistics
Inferring gene regulatory relationships with a high-dimensional robust approach
Conditional analysis of multiple quantitative traits based on marginal GWAS summary statistics
Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels
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Inclusion of biological knowledge in a Bayesian shrinkage model for joint estimation of SNP effects
A novel association test for multiple secondary phenotypes from a case-control GWAS
BinomiRare: A robust test of the association of a rare variant with a disease for pooled analysis and meta-analysis, with application to the HCHS/SOL
A genome‐wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study Mexican‐origin Americans / Mexican Americans
A combination test for detection of gene-environment interaction in cohort studies
Semiparametric methods for estimation of a nonlinear exposure‐outcome relationship using instrumental variables with application to Mendelian randomization
On the association analysis of genome‐sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows
Are rare variants really independent?
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gsSKAT: Rapid gene set analysis and multiple testing correction for rare‐variant association studies using weighted linear kernels
Genetic risk models: Influence of model size on risk estimates and precision
Gene‐based segregation method for identifying rare variants in family‐based sequencing studies
Adaptive testing for multiple traits in a proportional odds model with applications to detect SNP-brain network associations
Detecting association of rare and common variants based on cross-validation prediction error
Bayesian latent variable models for hierarchical clustered count outcomes with repeated measures in microbiome studies
A powerful statistical framework for generalization testing in GWAS, with application to the HCHS/SOL
Issue Information