| PEL: an unbiased method for estimating age‐dependent genetic disease risk from pedigree data unselected for family history |
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| Bayesian EM algorithm for scoring polymorphic deletions from SNP data and application to a common CNV on 8q24 |
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| Proper analysis of secondary phenotype data in case‐control association studies |
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| The limits of fine‐scale mapping |
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| Oral facial clefts and gene polymorphisms in metabolism of folate/one‐carbon and vitamin A: a pathway‐wide association study |
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| A critical evaluation of genomic control methods for genetic association studies |
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| A comparison of principal component analysis and factor analysis strategies for uncovering pleiotropic factors |
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| Allelic‐based gene‐gene interaction associated with quantitative traits |
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| Restricted parameter space models for testing gene‐gene interaction |
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| Relatedness mapping and tracts of relatedness for genome‐wide data in the presence of linkage disequilibrium |
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| Generalized linear modeling with regularization for detecting common disease rare haplotype association |
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| More powerful haplotype sharing by accounting for the mode of inheritance |
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| A likelihood ratio test of population Hardy‐Weinberg equilibrium for case‐control studies |
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| Ecogeographic genetic epidemiology |
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| Selection of the most informative individuals from families with multiple siblings for association studies |
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| Modifications to the Patient Rule‐Induction Method that utilize non‐additive combinations of genetic and environmental effects to define partitions that predict ischemic heart disease |
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✓ |
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European male participants |
| A polygenic model for integration of linkage and pathway information |
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| The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts |
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| Abstracts from the seventeenth annual meeting of the International Genetic Epidemiological Society |
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| Erratum |
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| Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations |
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| A multiple splitting approach to linkage analysis in large pedigrees identifies a linkage to asthma on chromosome 12 |
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| More powerful haplotype sharing by accounting for the mode of inheritance |
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| Power consequences of linkage disequilibrium variation between populations |
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| Genome‐wide autozygosity mapping in human populations |
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| Power comparisons between similarity‐based multilocus association methods, logistic regression, and score tests for haplotypes |
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| A hybrid design: case‐parent triads supplemented by control‐mother dyads |
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| A critique of the false‐positive report probability |
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| A new association test to test multiple‐marker association |
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| An optimal dose‐effect mode trend test for SNP genotype tables |
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| A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction |
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| Two‐stage analysis for gene‐environment interaction utilizing both case‐only and family‐based analysis |
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| Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects |
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| Common genetic influences underlie comorbidity of migraine and endometriosis |
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| Combined haplotype relative risk (CHRR): a general and simple genetic association test that combines trios and unrelated case‐controls |
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| Bayesian variable and model selection methods for genetic association studies |
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| A nonparametric method for penetrance function estimation |
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| Impaired performance of FDR‐based strategies in whole‐genome association studies when SNPs are excluded prior to the analysis |
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| CANDID: a flexible method for prioritizing candidate genes for complex human traits |
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| Multipoint lods provide reliable linkage evidence despite unknown limiting distribution: type I error probabilities decrease with sample size for multipoint lods and mods |
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| A partial least‐square approach for modeling gene‐gene and gene‐environment interactions when multiple markers are genotyped |
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| Bayes factors for genome‐wide association studies: comparison with<i>P</i>‐values |
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| A comparison of analytical methods for genetic association studies |
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| The ordered transmission disequilibrium test: detection of modifier genes |
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| Association mapping by generalized linear regression with density‐based haplotype clustering |
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| Comparison of association methods for dense marker data |
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| Measuring and partitioning the high‐order linkage disequilibrium by multiple order Markov chains |
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| A common cortactin gene variation confers differential susceptibility to severe asthma |
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✓ |
✓ |
✓ |
European descent; African Americans; African descent |
| Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds |
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| On the utility of gene set methods in genomewide association studies of quantitative traits |
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| A general method for linkage disequilibrium correction for multipoint linkage and association |
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| The power of independent types of genetic information to detect association in a case‐control study design |
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| Tests for gene‐environment interaction from case‐control data: a novel study of type I error, power and designs |
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| Ordered‐subset analysis (OSA) for family‐based association mapping of complex traits |
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| A prevalence‐based association test for case‐control studies |
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| On combining family and case‐control studies |
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| Assessing departure from Hardy‐Weinberg equilibrium in the presence of disease association |
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| Genetic association tests in the presence of epistasis or gene‐environment interaction |
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| Enhanced detection of genetic association of hypertensive heart disease by analysis of latent phenotypes |
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| Quantifying the contribution of genetic variants for survival phenotypes |
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| Analysis of multiple SNPs in a candidate gene or region |
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| On multiple‐testing correction in genome‐wide association studies |
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| CLUMPHAP: a simple tool for performing haplotype‐based association analysis |
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| Erratum |
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| Does strong linkage disequilibrium guarantee redundant association results? |
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| Inference from genome‐wide association studies using a novel Markov model |
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| Model‐based linkage analysis with imprinting for quantitative traits: ignoring imprinting effects can severely jeopardize detection of linkage |
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| Calculation of IBD probabilities with dense SNP or sequence data |
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| Fragile X‐associated primary ovarian insufficiency: evidence for additional genetic contributions to severity |
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✓ |
✓ |
race |
| Differential parental transmission of markers in <i>RUNX2</i> among cleft case‐parent trios from four populations |
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| Simple association analysis combining data from trios/sibships and unrelated controls |
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| Estimation of the multiple testing burden for genomewide association studies of nearly all common variants |
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✓ |
✓ |
✓ |
in Europeans; in Africans |
| Searching for epistasis and linkage heterogeneity by correlations of pedigree‐specific linkage scores |
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| Measuring and partitioning the high‐order linkage disequilibrium by multiple order Markov chains |
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| Using disease symptoms to improve detection of linkage under genetic heterogeneity |
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| Estimation of significance thresholds for genomewide association scans |
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✓ |
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| Genomewide scan of ocular refraction in African‐American families shows significant linkage to chromosome 7p15 |
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✓ |
✓ |
✓ |
European‐derived families; African‐American; African‐derived |
| X‐LRT: a likelihood approach to estimate genetic risks and test association with X‐linked markers using a case‐parents design |
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| Power of transmission/disequilibrium tests in admixed populations |
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| Genetic variants in <i>IRF6</i> and the risk of facial clefts: single‐marker and haplotype‐based analyses in a population‐based case‐control study of facial clefts in Norway |
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| Bivariate combined linkage and association mapping of quantitative trait loci |
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| A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms |
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| Testing association in the presence of linkage using the GRE and multiple markers |
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| Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men |
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✓ |
✓ |
Swedish men |
| Application of machine learning algorithms to predict coronary artery calcification with a sibship‐based design |
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✓ |
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| Evaluating cost efficiency of SNP chips in genome‐wide association studies |
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| Comparison of approaches for machine‐learning optimization of neural networks for detecting gene‐gene interactions in genetic epidemiology |
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| Maximizing association statistics over genetic models |
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| On the analysis of copy‐number variations in genome‐wide association studies: a translation of the family‐based association test |
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| An ensemble learning approach jointly modeling main and interaction effects in genetic association studies |
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| Relationship uncertainty linkage statistics (RULS): affected relative pair statistics that model relationship uncertainty |
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| Increasing the power of identifying gene × gene interactions in genome‐wide association studies |
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| Genome‐wide admixture mapping for coronary artery calcification in African Americans: the NHLBI Family Heart Study |
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✓ |
✓ |
✓ |
"European American" and "European and African ancestries among African Americans"; "African American", "Africans", and "European American" |
| Genome‐wide significance for dense SNP and resequencing data |
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✓ |
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European populations |