Familial Cancer - 2015

85 articles | Last updated: 2025-12-03 14:12:56
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Initial clinical validation of Health Heritage, a patient-facing tool for personal and family history collection and cancer risk assessment
Recurrent candidiasis and early-onset gastric cancer in a patient with a genetically defined partial MYD88 defect
Gatekeeper role of gastroenterologists and surgeons in recognising and discussing familial colorectal cancer
Risk of thyroid cancer among Caribbean Hispanic patients with familial adenomatous polyposis
Mutation analysis of MUTYH in Japanese colorectal adenomatous polyposis patients
Determining the familial risk distribution of colorectal cancer: a data mining approach
Mismatch repair deficiency concordance between primary colorectal cancer and corresponding metastasis
Associations between allergic conditions and pediatric brain tumors in Neurofibromatosis type 1
Screening of the BRCA1 gene in Brazilian patients with breast and/or ovarian cancer via high-resolution melting reaction analysis
Non-genetic health professionals’ attitude towards, knowledge of and skills in discussing and ordering genetic testing for hereditary cancer
Erratum to: Methylation of the miR-126 gene associated with glioma progression
Are lung cysts in renal cell cancer (RCC) patients an indication for FLCN mutation analysis?
Development of a novel PTT assay for mutation detection in PALB2 large exons and PALB2 screening in medullary breast cancer
Correlation between the germline methylation status in ERβ promoter and the risk in prostate cancer: a prospective study
CYP1A1 and GSTP1 gene variations in breast cancer: a systematic review and case–control study
Diagnostic values of osteopontin combined with CA125 for ovarian cancer: a meta-analysis
Methylation of the miR-126 gene associated with glioma progression
Surveillance using capsule endoscopy is safe in post-colectomy patients with familial adenomatous polyposis: a prospective Japanese study
Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary
Genetic testing for Lynch syndrome: family communication and motivation
Germline TERT promoter mutations are rare in familial melanoma
Association between the FTOrs8050136 polymorphism and cancer risk: a meta-analysis
Aortopulmonary window parathyroid gland causing primary hyperparathyroidism in men type 1 syndrome
First report of somatic mosaicism for mutations in STK11 in four patients with Peutz–Jeghers syndrome
Is there an association between invasive lobular carcinoma of the breast and a family history of gastric cancer?
Screening of HELQ in breast and ovarian cancer families
Birt–Hogg–Dubé syndrome: novel FLCN frameshift deletion in daughter and father with renal cell carcinomas
Rhabdoid tumor predisposition syndrome caused by SMARCB1 constitutional deletion: prenatal detection of new case of recurrence in siblings due to gonadal mosaicism
The knowledge value-chain of genetic counseling for breast cancer: an empirical assessment of prediction and communication processes
Association of APC I1307K and E1317Q polymorphisms with colorectal cancer among Egyptian subjects
The role of germline mutations in the BRCA1/2 and mismatch repair genes in men ascertained for early-onset and/or familial prostate cancer
Ovarian tumors related to intronic mutations in DICER1: a report from the international ovarian and testicular stromal tumor registry
Incidental diagnosis of HLRCC following investigation for Asperger Syndrome: actionable and actioned
Long-term outcome of sporadic and FAP-associated desmoid tumors treated with high-dose selective estrogen receptor modulators and sulindac: a single-center long-term observational study in 134 patient
Screening of RET gene mutations in Chinese patients with medullary thyroid carcinoma and their relatives Chinese
POLE mutations in families predisposed to cutaneous melanoma
The effect of personal medical history and family history of cancer on the uptake of risk-reducing salpingo-oophorectomy
Risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a 30-year semi-prospective analysis
Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene
Risk reducing salpingectomy and delayed oophorectomy in high risk women: views of cancer geneticists, genetic counsellors and gynaecological oncologists in the UK
Massive gastric polyposis associated with a germline SMAD4 gene mutation
Metastatic sympathetic paraganglioma in a patient with loss of the SDHC gene
Challenges to clinical utilization of hereditary cancer gene panel testing: perspectives from the front lines
High accuracy of family history of melanoma in Danish melanoma cases
BRCA1 gene variant p.P142H associated with male breast cancer: a two-generation genealogic study and literature review
Supporting families with Cancer: A patient centred survivorship model of care
Coexistence of paraganglioma/pheochromocytoma and papillary thyroid carcinoma: a four-case series analysis
Follicular variant of papillary thyroid cancer in Alström syndrome
BRCA1 and BRCA2 mutations in males with familial breast and ovarian cancer syndrome. Results of a Spanish multicenter study
A functional HOTAIR rs920778 polymorphism does not contributes to gastric cancer in a Turkish population: a case–control study Turkish population
International society for gastrointestinal hereditary tumours—InSiGHT
Psychological distress related to BRCA testing in ovarian cancer patients
Prevalence and detection of psychosocial problems in cancer genetic counseling
Survival in familial colorectal cancer: a Danish cohort study
Childhood cancers in families with and without Lynch syndrome
Genotype–phenotype analysis of von Hippel–Lindau syndrome in fifteen Indian families
Birt–Hogg–Dubé syndrome and intracranial vascular pathologies
3′-UTR poly(T/U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer with nearly perfect sensitivity
Zebrafish xenotransplantation as a tool for in vivo cancer study
A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine
Specific Alu elements involved in a significant percentage of copy number variations of the STK11 gene in patients with Peutz–Jeghers syndrome
Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study
Increased risk for colorectal adenomas and cancer in mono-allelic MUTYH mutation carriers: results from a cohort of North-African Jews North-African Jews
Erratum to: Mutations of HNRNPA0 and WIF1 predispose members of a large family to multiple cancers
Implementing a telephone based peer support intervention for women with a BRCA1/2 mutation
Germline mutations predisposing to non-small cell lung cancer
Validation of an online questionnaire for identifying people at risk of familial and hereditary colorectal cancer
Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome
Pitfalls in the diagnosis of biallelic PMS2 mutations
Genetic screening in patients with Retinoblastoma in Israel
The analysis of a large Danish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 11q24
Mutations of HNRNPA0 and WIF1 predispose members of a large family to multiple cancers
The importance of proper bioinformatics analysis and clinical interpretation of tumor genomic profiling: a case study of undifferentiated sarcoma and a constitutional pathogenic BRCA2 mutation and an
Heterozygous germline mutations in NBS1 among Korean patients with high-risk breast cancer negative for BRCA1/2 mutation
Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study
Large genomic rearrangements in the familial breast and ovarian cancer gene BRCA1 are associated with an increased frequency of high risk features
Polymorphisms of the XRCC1 gene and breast cancer risk in the Mexican population
Analysis of PALB2 in a cohort of Italian breast cancer patients: identification of a novel PALB2 truncating mutation
Defective DNA mismatch repair activity is common in sebaceous neoplasms, and may be an ineffective approach to screen for Lynch syndrome
The effect of oral 3,3′-diindolylmethane supplementation on the 2:16α-OHE ratio in BRCA1 mutation carriers
High-resolution melting (HRM) re-analysis of a polyposis patients cohort reveals previously undetected heterozygous and mosaic APC gene mutations
Germline RAD51B truncating mutation in a family with cutaneous melanoma
Exome sequencing reveals three novel candidate predisposition genes for diffuse gastric cancer
The breast cancer immunophenotype of TP53-p.R337H carriers is different from that observed among other pathogenic TP53 mutation carriers
A risk of digestive tract neoplasms susceptibility in miR-146a and miR-196a2