| Intra-family phenotypic heterogeneity of 16p11.2 deletion carriers in a three-generation Chinese family |
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| Genome-wide association study of hoarding traits |
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| Linkage and association on 8p21.2-p21.1 in schizophrenia |
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| Cognitive effects of genetic variation in monoamine neurotransmitter systems: A population‐based study of
<i>COMT</i>
,
<i>MAOA</i>
, and
<i |
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| Fine mapping of candidate regions for bipolar disorder provides strong evidence for susceptibility loci on chromosomes 7q |
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| The
<i>ATXN1</i>
and
<i>TRIM31</i>
genes are related to intelligence in an ADHD background: Evidence from a large collaborative study totaling 4,963 Sub |
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| “Replicated” genome wide association for dependence on illegal substances: Genomic regions identified by overlapping clusters of nominally positive SNPs |
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| Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders |
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| Copy number variation characteristics in subpopulations of patients with autism spectrum disorders |
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| Parent-of-origin effects of the serotonin transporter gene associated with autism |
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| Gene–environment interactions in panic disorder and CO<sub>2</sub> sensitivity: Effects of events occurring early in life |
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| Heritability estimates for psychotic symptom dimensions in twins with psychotic disorders |
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| Exon expression and alternatively spliced genes in tourette syndrome |
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| From the black widow spider to human behavior: Latrophilins, a relatively unknown class of G protein‐coupled receptors, are implicated in psychiatric disorders |
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| Screening of human <i>LPHN3</i> for variants with a potential impact on ADHD susceptibility |
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| Factors associated with experiences of genetic discrimination among individuals at risk for huntington disease |
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|
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| Association of <i>RANBP1</i> haplotype with smooth pursuit eye movement abnormality |
|
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|
|
✓ |
✓ |
Korean population |
| Genome‐wide association study of theta band event‐related oscillations identifies serotonin receptor gene<i>HTR7</i>influencing risk of alcohol dependence |
|
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|
| Increased symptoms of attention deficit hyperactivity disorder and major depressive disorder symptoms in nail‐patella syndrome: Potential association with <i>LMX1B</i> loss‐of‐function |
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|
| Family‐based genetic association study of <i>DLGAP3</i> in Tourette Syndrome |
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|
| Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21 |
|
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|
|
✓ |
✓ |
German population |
| Lack of association between G‐protein coupled receptor kinase 5 gene and Parkinson's disease |
|
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|
|
|
✓ |
✓ |
Japanese population; Southern Italy |
| Genetic analysis of “leucine‐rich repeat (LRR) and immunoglobulin (Ig) domain‐containing, Nogo receptor‐interacting protein‐1 (<i>LINGO1</i>)” in two independent Chinese parkinson's disease population |
|
|
|
|
|
|
✓ |
✓ |
ethnic Chinese populations |
| Effect of dopamine transporter genotype on caudate volume in childhood ADHD and controls |
|
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|
|
| Effects of the BDNF val66met polymorphism on prefrontal brain function in a population at high genetic risk of schizophrenia |
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|
| The impact of a genome‐wide supported psychosis variant in the <i>ZNF804A</i> gene on memory function in schizophrenia |
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|
|
| Fine‐mapping reveals novel alternative splicing of the dopamine transporter |
|
✓ |
|
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|
|
| Childhood maltreatment, the corticotropin‐releasing hormone receptor gene and adult depression in the general population |
|
✓ |
|
|
|
|
✓ |
✓ |
German general population |
| Effects of the A(−115)G variant on <i>CREB1</i> promoter activity in two brain cell lines: Interactions with gonadal steroids |
|
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|
| European collaborative study of early‐onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset |
|
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|
✓ |
✓ |
|
|
European families |
| L‐type calcium channels and psychiatric disorders: A brief review |
|
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|
| A genomewide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12 |
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| Genetic variability in estrogen disposition: Potential clinical implications for neuropsychiatric disorders |
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| Risk gene variants for nicotine dependence in the <i>CHRNA5</i>–<i>CHRNA3</i>–<i>CHRNB4</i> cluster are associated with cognitive performance |
|
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|
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|
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|
|
| No evidence that rare coding variants in<i>ZNF804A</i>confer risk of schizophrenia |
|
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|
|
| Polymorphisms of the steroid sulfatase (<i>STS</i>) gene are associated with attention deficit hyperactivity disorder and influence brain tissue mRNA expression |
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| Rare genotype combination of the serotonin transporter gene associated with treatment response in severe personality disorder |
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|
| Older paternal age strongly increases the morbidity for schizophrenia in sisters of affected females |
|
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|
|
| <i>EGR3</i> as a potential susceptibility gene for schizophrenia in Korea |
|
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|
| No association between <i>MTHFR</i> C677T or A1298C and age at onset of schizophrenia: Comments |
|
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|
|
| Genetic analysis of nitric oxide synthase 1 variants in schizophrenia and bipolar disorder |
|
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|
|
| Analysis of GWAS top hits in ADHD suggests association to two polymorphisms located in genes expressed in the cerebellum |
|
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|
|
| Response to “Dizziness Genes” |
|
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|
|
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|
|
| No association between MTHFR C677T or A1298C and age at onset of schizophrenia |
|
|
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|
|
| No major role for X‐inactivation in variations of intelligence and behavioral problems at middle childhood |
|
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|
|
| Maternal smoking during pregnancy is associated with epigenetic modifications of the brain‐derived neurotrophic factor‐6 exon in adolescent offspring |
|
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|
|
| Variation at the GABA<sub>A</sub> receptor gene, Rho 1 (<i>GABRR1</i>) associated with susceptibility to bipolar schizoaffective disorder |
|
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|
|
| Accuracy of phenotyping of autistic children based on internet implemented parent report |
|
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|
|
| The refinement of the critical region for the 2q31.2q32.3 deletion syndrome indicates candidate genes for mental retardation and speech impairment |
|
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|
|
| The Bipolar Association Case–Control Study (BACCS) and meta‐analysis: No association with the 5,10‐Methylenetetrahydrofolate reductase gene and bipolar disorder |
|
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|
|
|
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|
|
| Identification of a novel genetic locus on chromosome 8p21.1–q11.23 for idiopathic basal ganglia calcification |
|
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|
|
| Dizziness genes |
|
|
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|
|
| Positive symptoms of psychosis correlate with expression of ubiquitin proteasome genes in peripheral blood |
|
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|
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|
|
| Testing for genetic association between the <i>ZDHHC8</i> gene locus and <i>susceptibility</i> to schizophrenia: An integrated analysis of multiple datasets |
|
|
|
|
|
|
✓ |
✓ |
"East Asian populations"; "ethnic populations"; "ancestry" |
| Association analysis of <i>PALB2</i> and <i>BRCA2</i> in bipolar disorder and schizophrenia in a scandinavian case–control sample |
|
|
|
|
|
|
✓ |
✓ |
Scandinavian; Nordic; Iceland |
| Somatic mosaicism in a case of apparently sporadic Creutzfeldt‐Jakob disease carrying a de novo D178N mutation in the <i>PRNP</i> gene |
|
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|
|
|
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|
|
| An investigation of candidate regions for association with bipolar disorder |
|
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|
|
|
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|
|
| Psychiatric and behavioral manifestations of lysosomal storage disorders |
|
|
|
|
|
|
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|
|
| Failure to confirm genetic association of the <i>FXYD6</i> gene with schizophrenia: The Japanese population and meta‐analysis |
|
|
|
|
|
|
✓ |
✓ |
Japanese population; ethnically homogeneous Japanese population; UK samples |
| Genome‐scan for bipolar disorder with sib‐pair families in the Sardinian population: A new susceptibility locus on chromosome 1p22–p21? |
|
|
|
|
|
|
✓ |
✓ |
Sardinian population; "Sardinian population presents a peculiar genetic homogeneity" |
| A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism |
|
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|
|
|
|
|
|
|
| Further investigation of the association between rs7341475 and rs17746501 and schizophrenia |
|
|
|
|
|
|
✓ |
✓ |
Ashkenazi Jews (AJ) |
| Meta‐analysis of the heterogeneity in association of DRD4 7‐repeat allele and AD/HD: Stronger association with AD/HD combined type |
|
|
|
|
|
|
|
|
|
| Identical but not the same: The value of discordant monozygotic twins in genetic research |
|
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|
|
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|
|
| Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts |
|
|
|
|
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|
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|
|
| The DRD4 receptor Exon 3 VNTR and 5′ SNP variants and mRNA expression in human post‐mortem brain tissue |
|
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|
|
|
|
|
|
|
| Coming to grips with complex disorders: Genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics |
|
|
|
|
|
✓ |
✓ |
✓ |
European‐American; African‐American |
| In their own words: Reports of stigma and genetic discrimination by people at risk for Huntington disease in the International RESPOND‐HD study |
|
|
|
|
|
|
|
|
|
| <i>LINGO1</i> is not associated with Parkinson's disease in German patients |
|
|
|
|
|
|
|
|
|
| Analysis of the <i>Micro‐RNA‐133</i> and <i>PITX3</i> genes in Parkinson's disease |
|
|
|
|
|
|
|
|
|
| <i>PCM1</i> and schizophrenia: A replication study in the Northern Swedish population |
|
|
|
|
|
|
✓ |
✓ |
UK/Scottish population; Northern Swedish population |
| Deletions of <i>NRXN1</i> (neurexin‐1) predispose to a wide spectrum of developmental disorders |
|
|
|
|
|
|
|
|
|
| Association of <i>ZDHHC8</i> polymorphisms with smooth pursuit eye movement abnormality |
|
|
|
|
|
|
✓ |
✓ |
Korean population |
| Association between CYP2C19 polymorphism and depressive symptoms |
|
|
|
|
|
✓ |
|
|
1,472 subjects of European ancestry (45–98 years old) from the Swedish Twin Registry. |
| Association study of 182 candidate genes in anorexia nervosa |
|
|
|
|
|
|
|
|
|
| Intra‐individual variability in genetic and environmental models of attention‐deficit/hyperactivity disorder |
|
|
|
|
|
|
|
|
|
| No association of the serotonin transporter polymorphisms 5‐HTTLPR and RS25531 with schizophrenia or neurocognition |
|
|
|
|
|
|
✓ |
✓ |
ancestry‐informative principal components; ancestry |
| Case–control association study of <i>TGOLN2</i> in attempted suicide |
|
|
|
|
|
|
|
|
|
| Genetic pathway‐based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes |
|
|
|
|
|
|
|
|
|
| Perception, experience, and response to genetic discrimination in Huntington disease: The international RESPOND‐HD study |
|
|
|
|
|
|
|
|
|
| Severe mental retardation, seizures, and hypotonia due to deletions of <i>MEF2C</i> |
|
|
|
|
|
|
|
|
|
| Evidence for three loci modifying age‐at‐onset of Alzheimer's disease in early‐onset <i>PSEN2</i> families |
|
|
|
|
|
|
|
|
|
| A new susceptibility locus for bipolar affective disorder in PAR1 on Xp22.3/Yp11.3 |
|
|
|
|
|
|
✓ |
✓ |
German and Spanish origin |
| A functional variant provided further evidence for the association of <i>ARVCF</i> with schizophrenia |
|
|
|
|
|
|
|
|
|
| No association of alcohol dependence with HOMER 1 and 2 genetic variants |
|
|
|
|
|
|
|
|
|
| The <i>P</i>‐value illusion: How to improve (psychiatric) genetic studies |
|
|
|
|
|
|
|
|
|
| BDNF Val66Met polymorphism alters sympathovagal balance in healthy subjects |
|
|
|
|
|
|
✓ |
✓ |
Chinese‐Han |
| Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations |
|
✓ |
|
|
✓ |
✓ |
|
|
European Caucasian samples; European populations |
| Intragenic rearrangements in <i>NRXN1</i> in three families with autism spectrum disorder, developmental delay, and speech delay |
|
|
|
|
|
|
|
|
|
| Limited genetic covariance between autistic traits and intelligence: Findings from a longitudinal twin study |
|
|
|
|
|
|
|
|
|
| SNPs in CAST are associated with Parkinson disease: A confirmation study |
|
|
|
|
|
|
|
|
|
| Analysis of whole genome biomarker expression in blood and brain |
|
|
|
|
|
|
|
|
|
| Sexually dimorphic interaction between the <i>DRD1</i> and <i>COMT</i> genes in schizophrenia |
|
|
|
|
|
|
|
|
|
| High frequency of multiexonic deletion of the <i>GCH1</i> gene in a Taiwanese cohort of dopa‐response dystonia |
|
|
|
|
|
|
✓ |
✓ |
Taiwanese; Han Chinese ethnicity |
| Functional variants of <i>TSPAN8</i> are associated with bipolar disorder and schizophrenia |
|
|
|
|
|
|
|
|
|
| Failure to confirm association between <i>PIK4CA</i> and psychosis in 22q11.2 deletion syndrome |
|
|
|
|
|
|
|
|
|
| Heritability estimates for cognitive factors and brain white matter integrity as markers of schizophrenia |
|
|
|
|
|
|
|
|
|
| A megalin polymorphism associated with promoter activity and Alzheimer's disease risk |
|
|
|
|
|
|
|
|
|
| Simultaneous analysis of serotonin transporter, tryptophan hydroxylase 1 and 2 gene expression in the ventral prefrontal cortex of suicide victims |
|
|
|
|
|
|
|
|
|
| Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease |
|
|
|
|
|
✓ |
|
|
three European and European American populations |
| A co‐segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder |
|
|
|
|
|
|
✓ |
✓ |
Dutch |
| A systematic association mapping on chromosome 6q in bipolar affective disorder—evidence for the <i>melanin‐concentrating‐hormone‐receptor‐2</i> gene as a risk factor for bipolar affective disorder |
|
|
|
|
|
|
✓ |
✓ |
"German descent"; "ethnically matched" |
| Association study of <i>SNAP25</i> and schizophrenia in Irish family and case–control samples |
|
|
|
|
|
|
✓ |
✓ |
Irish |
| The effect of smoking on <i>MAOA</i> promoter methylation in DNA prepared from lymphoblasts and whole blood |
|
|
|
|
|
|
|
|
|
| Evidence for the involvement of genetic variation in the <i>oxytocin receptor</i> gene (<i>OXTR</i>) in the etiology of autistic disorders on high‐functioning level |
|
|
|
|
|
|
|
|
|
| Linkage analysis of Tourette syndrome in a large utah pedigree |
|
|
|
|
|
|
|
|
|
| Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa? |
|
|
|
|
|
|
|
|
|
| Association between methylenetetrahydrofolate reductase (<i>MTHFR</i>) C677T polymorphism and age of onset in schizophrenia |
|
|
|
|
|
|
✓ |
✓ |
Scandinavian; Chinese |
| The association of the dopamine transporter gene and the dopamine receptor 2 gene with delirium, a meta‐analysis |
|
|
|
|
|
✓ |
|
|
Six European populations collected DNA of older delirious patients. |
| Methylation at <i>SLC6A4</i> is linked to family history of child abuse: An examination of the Iowa Adoptee sample |
|
|
|
|
|
|
|
|
|
| <i>G72</i> influences longitudinal change in frontal lobe volume in schizophrenia |
|
|
|
|
|
|
|
|
|
| Novel mutations in the calreticulin gene core promoter and coding sequence in schizoaffective disorder |
|
|
|
|
|
|
|
|
|
| Association of <i>CHRN</i> genes with “dizziness” to tobacco |
|
|
|
|
|
|
|
|
|
| No association of dysbindin with symptom factors of schizophrenia in an Irish case–control sample |
|
|
|
|
|
|
|
|
|
| Significant association between the C(−1019)G functional polymorphism of the HTR<sub>1A</sub> gene and impulsivity |
|
|
|
|
|
|
|
|
|
| Support of association between <i>BRD1</i> and both schizophrenia and bipolar affective disorder |
|
✓ |
|
|
|
|
✓ |
✓ |
Scottish population; Denmark and England (UK/DK sample); UCL sample (English sample) |
| <i>PER2</i> variantion is associated with depression vulnerability |
|
|
|
|
|
|
✓ |
✓ |
Swedish population-based sample |
| Sex‐specific association of the reelin gene with bipolar disorder |
|
|
|
|
|
|
|
|
|
| Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention‐deficit/hyperactivity disorder |
|
|
|
|
|
✓ |
|
|
all of European descent |
| Common origin of pure and interrupted repeat expansions in spinocerebellar ataxia type 2 (SCA2) |
|
|
|
|
|
✓ |
|
|
older European ancestry |
| Reduced 3‐<i>O</i>‐methyl‐dopa levels in OCD patients and their unaffected parents is associated with the low activity M158 COMT allele |
|
|
|
|
|
|
|
|
|
| FKBP5 polymorphisms and antidepressant response in geriatric depression |
|
|
|
|
|
|
|
|
|
| Association studies of −3081(A/T) polymorphism of norepinephrine transporter gene with attention deficit/hyperactivity disorder in Korean population |
|
|
|
|
|
|
✓ |
✓ |
Korean population |
| The P86L common allele of <i>CALHM1</i> does not influence risk for Alzheimer disease in Japanese cohorts |
|
✓ |
|
|
|
✓ |
✓ |
✓ |
individuals of European‐descent; non‐Caucasian populations; Caucasians |
| Interaction among genes influencing ethanol metabolism and sex is association with alcohol use disorders in a Tibet population |
|
|
|
|
|
|
✓ |
✓ |
Tibetan population |
| Association of a variant in the muscarinic acetylcholine receptor 2 gene (<i>CHRM2</i>) with nicotine addiction |
|
|
|
|
|
|
✓ |
✓ |
German population; western countries |
| Behavioral phenotype in the 9q subtelomeric deletion syndrome: A report about two adult patients |
|
|
|
|
|
|
|
|
|
| Meta‐analysis of brain‐derived neurotrophic factor p.Val66Met in adult ADHD in four European populations |
|
|
|
|
✓ |
|
|
|
European populations |
| Association and gene–gene interaction of <i>SLC6A4</i> and <i>ITGB3</i> in autism |
|
|
|
|
|
|
|
|
|
| Preliminary evidence of ubiquitin proteasome system dysregulation in schizophrenia and bipolar disorder: Convergent pathway analysis findings from two independent samples |
|
|
|
|
|
|
|
|
|
| Investigation of an epistastic effect between a set of TAAR6 and HSP‐70 genes variations and major mood disorders |
|
|
|
|
|
|
|
|
|
| Variation in <i>GRIN2B</i> contributes to weak performance in verbal short‐term memory in children with dyslexia |
|
|
|
|
|
|
✓ |
✓ |
German dyslexia sample |
| D10S1423 identifies a susceptibility locus for Alzheimer's disease (<i>AD7</i>) in a prospective, longitudinal, double‐blind study of asymptomatic individuals: Results at 14 years |
|
|
|
|
|
|
|
|
|
| Association of reading disabilities with regions marked by acetylated H3 histones in <i>KIAA0319</i> |
|
|
|
|
|
|
|
|
|
| Impact of Neuritin 1 (<i>NRN1</i>) polymorphisms on fluid intelligence in schizophrenia |
|
|
|
|
|
|
|
|
|
| A screen of SLC1A1 for OCD‐related alleles |
|
|
|
|
|
|
✓ |
✓ |
ethnically matched controls |
| <i>APOE</i> mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure |
|
|
|
|
|
|
|
|
|
| Association analyses between brain‐expressed fatty‐acid binding protein (<i>FABP</i>) genes and schizophrenia and bipolar disorder |
|
|
|
|
|
|
|
|
|
| CAG‐repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approaches |
|
|
|
|
|
|
|
|
|
| A longitudinal follow‐up study of autistic symptoms in children and adults with duplications of 15q11‐13 |
|
|
|
|
|
|
|
|
|
| A population‐based association study of candidate genes for depression and sleep disturbance |
|
|
|
|
|
|
|
|
|
| Association of <i>MET</i> with social and communication phenotypes in individuals with autism spectrum disorder |
|
|
|
|
|
|
|
|
|
| <i>GABRR1</i>and<i>GABRR2</i>, encoding the GABA‐A receptor subunits ρ1 and ρ2, are associated with alcohol dependence |
|
|
|
|
|
✓ |
|
|
European Americans |
| <i>ADH1A</i> variation predisposes to personality traits and substance dependence |
|
|
|
|
|
✓ |
✓ |
✓ |
European‐Americans; European‐origin Hispanics; African‐Americans |
| The tryptophan hydroxylase 1 (<i>TPH1</i>) gene, schizophrenia susceptibility, and suicidal behavior: A multi‐centre case–control study and meta‐analysis |
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