| Human QKI, a new candidate gene for schizophrenia involved in myelination |
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| Genotypic interaction between DRD4 and DAT1 loci is a high risk factor for attention‐deficit/hyperactivity disorder in Chilean families |
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| Maternal age at the birth of the first child as an epistatic factor in polygenic disorders |
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| Genetic liability to schizophrenia or bipolar disorder and its relationship to brain structure |
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| Association study of a functional promoter polymorphism in the<i>XBP1</i>gene and schizophrenia |
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✓ |
✓ |
✓ |
European case‐control samples; European populations; Asian subjects |
| Association of dopamine D4 receptor (DRD4) polymorphisms with attention deficit hyperactivity disorder in Indian population |
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✓ |
✓ |
Indian; different ethnic groups; Indian subjects; Indian ADHD children |
| Expression and genetic variability of <i>PCDH11Y</i>, a gene specific to <i>Homo sapiens</i> and candidate for susceptibility to psychiatric disorders |
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✓ |
✓ |
ethnically‐matched control populations |
| Automated sequence screening of the entire dystrophin cdna in Duchenne dystrophy: Point mutation detection |
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| Association of the phosphatase and tensin homolog gene (PTEN) with smoking initiation and nicotine dependence |
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| Genomewide scan for real‐word reading subphenotypes of dyslexia: Novel chromosome 13 locus and genetic complexity |
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| Complete maternal uniparental isodisomy of chromosome 4 in a subject with major depressive disorder detected by high density SNP genotyping arrays |
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✓ |
✓ |
Portuguese population |
| Analysis of polymorphisms in AT‐rich domains of neuregulin 1 gene in schizophrenia |
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✓ |
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| Genetic etiology of stability of attention problems in young adulthood |
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| Prion genotypes in Central America suggest selection for the V129 allele |
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✓ |
✓ |
South American populations; East Asian populations |
| A preliminary comparison of the hopes of researchers, clinicians, and families for the future ethical use of genetic findings on schizophrenia |
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| Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder |
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| Association of a functional serotonin transporter gene polymorphism with binge eating disorder |
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| Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia |
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| Erratum |
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| Adenosine A<sub>2A</sub> receptor dysfunction correlates with age at onset anticipation in blood platelets of subjects with Huntington's disease |
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| Haplotype diversity and somatic instability in normal and expanded SCA8 alleles |
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✓ |
✓ |
Portuguese |
| Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependence |
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✓ |
✓ |
African descent |
| Abnormal elevation of<i>FMR1</i>mRNA is associated with psychological symptoms in individuals with the fragile X premutation |
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| XIII World Congress on Psychiatric Genetics 2005 |
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| Confirmation of association between the Val66Met polymorphism in the brain‐derived neurotrophic factor (<i>BDNF</i>) gene and bipolar I disorder |
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✓ |
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European descent |
| Evidence of genetic overlap of schizophrenia and bipolar disorder: Linkage disequilibrium analysis of chromosome 18 in the Costa Rican population |
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| Genome scan of schizophrenia families in a large Veterans Affairs Cooperative Study sample: Evidence for linkage to 18p11.32 and for racial heterogeneity on chromosomes 6 and 14 |
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✓ |
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European American (EA) |
| Haplotype‐controlled analysis of the association of a non‐synonymous single nucleotide polymorphism at <i>DBH</i> (+ 1603C → T) with plasma dopamine β‐hydroxylase activity |
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✓ |
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subjects of European origin |
| Linkage analysis of anorexia and bulimia nervosa cohorts using selected behavioral phenotypes as quantitative traits or covariates |
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| Selection of eating‐disorder phenotypes for linkage analysis |
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| Significant association of <i>BDNF</i> haplotypes in European‐American male smokers but not in European‐American female or African‐American smokers |
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✓ |
✓ |
✓ |
✓ |
European‐American; African‐American |
| Transmission disequilibrium suggests a role for the sulfotransferase‐4A1 gene in schizophrenia |
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| Haplotype analysis of the <i>COMT</i>‐<i>ARVCF</i> gene region in Israeli anorexia nervosa family trios |
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✓ |
✓ |
Israeli-Jewish population; Israeli |
| Interindividual variation in anxiety response to amphetamine: Possible role for adenosine A<sub>2A</sub> receptor gene variants |
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| DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters |
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| Failure to confirm association between RGS4 haplotypes and schizophrenia in Caucasians |
✓ |
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| Sequence variation in the 3′‐untranslated region of the dopamine transporter gene and attention‐deficit hyperactivity disorder (ADHD) |
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| Analysis of the <i>SREBF2</i> gene as a genetic risk factor for vascular dementia |
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| Association studies of transforming growth factor‐β1 and Alzheimer's disease |
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| No support for association between the dopamine transporter (<i>DAT</i>1) gene and ADHD |
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| Transmission disequilibrium and haplotype analyses of the G72/G30 locus: Suggestive linkage to schizophrenia in Palestinian Arabs living in the North of Israel |
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✓ |
✓ |
Ashkenazi, Palestinian Arab, French Canadian, Russian |
| Family‐based association study of the serotonin transporter gene polymorphisms in Korean ADHD trios |
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✓ |
✓ |
East Asian; Korean |
| Family‐based association study of serotonin transporter gene polymorphisms in attention deficit hyperactivity disorder: No evidence for association in UK and Taiwanese samples |
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| Neuregulin‐1 polymorphism in late onset Alzheimer's disease families with psychoses |
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| Direct genomic PCR sequencing of the high affinity thiamine transporter (SLC19A2) gene identifies three genetic variants in Wernicke Korsakoff syndrome (WKS) |
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| Association study ofCREB1 and childhood-onset mood disorders |
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| Association of the promoter polymorphism −1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa |
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| Cytosolic PLA2 genes possibly contribute to the etiology of schizophrenia |
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| 5-HT1A polymorphism and self-transcendence in mood disorders |
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| An association analysis of microsatellite markers across the Prader-Willi/Angelman critical region on chromosome 15 (q11-13) and autism spectrum disorder |
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| Insomnia improvement during antidepressant treatment andCLOCK gene polymorphism |
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| Evidence for a common biological basis of the absorption trait, hallucinogen effects, and positive symptoms: Epistasis between 5-HT2a and COMT polymorphisms |
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| Population-based and family-based association study of 5′UTR polymorphism of the reelin gene and schizophrenia |
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| Functional COMT variant predicts response to high dose pyridoxine in Parkinson's disease |
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| Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease |
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| A high predisposition to depression and anxiety in mothers and other matrilineal relatives of children with presumed maternally inherited mitochondrial disorders |
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| Addendum |
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| The biography of psychiatric genetics: From early achievements to historical burden, from an anxious society to critical geneticists |
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| Disruption of a brain transcription factor, NPAS3, is associated with schizophrenia and learning disability |
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| Apolipoprotein E4 is probably responsible for the chromosome 19 linkage peak for Parkinson's disease |
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| ISPG lifetime achievement award 2004 |
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| Genomewide linkage scan for cocaine dependence and related traits: Significant linkages for a cocaine-related trait and cocaine-induced paranoia |
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| Linkage and candidate gene analysis of 14q22-24 in bipolar disorder: support for GCHI as a novel susceptibility gene |
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| <i>DRD4</i>gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): Effects of associated alleles at the VNTR and −521 SNP |
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| A family study of early-onset obsessive-compulsive disorder |
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| Evaluation of the chromosome 2q37.3 gene<i>CENTG2</i>as an autism susceptibility gene |
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| Dendritic spine abnormalities in the occipital cortex of C57BL/6Fmr1 knockout mice |
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| Morbid risk for psychiatric disorder among the relatives of methamphetamine users with and without psychosis |
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| XBP1 gene polymorphism (-116C/G) and personality |
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| Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approache |
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| Sequence variants of theDRD4 gene in autism: Further evidence that rareDRD4 7R haplotypes are ADHD specific |
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| Serotonin transporter: Evolution and impact of polymorphic transcriptional regulation |
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| Mutation screening of a haplotype block around the insulin degrading enzyme gene and association with Alzheimer's disease |
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| Relationship of serotonin transporter gene polymorphisms and haplotypes to mRNA transcription |
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| Dihydropyrimidinase-related protein 2 (DRP-2) gene and association to deficit and nondeficit schizophrenia |
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| Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme |
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| Only tryptophan hydroxylase (TPH)-2 is relevant to the CNS |
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| Response to Dr. Kopke's comments on haplotypes at the OPRM1 locus |
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| Mutational screening and association study of glutamate decarboxylase 1 as a candidate susceptibility gene for bipolar affective disorder and schizophrenia |
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| Association of the apolipoprotein A‐IV: 360 gln/his polymorphism with cerebrovascular disease, obesity, and depression in a Brazilian elderly population |
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| Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment |
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| Genome‐wide linkage analyses of extended Utah pedigrees identifies loci that influence recurrent, early‐onset major depression and anxiety disorders |
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| Henrik Lykke Ewald (1958–2004) |
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| Hyperhomocysteinemia, methylenetetrahydrofolate reductase 677TT genotype, and the risk for schizophrenia: A dutch population based case‐control study |
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|
Dutch ancestry |
| Toward localizing genes underlying cerebral asymmetry and mental health |
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| Association of the serotonin transporter promoter polymorphism with smoking behavior among adolescents |
|
✓ |
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| Association analysis of the dopamine transporter (<i>DAT1</i>)‐67A/T polymorphism in bipolar disorder |
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| Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region |
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| Possible association between autism and variants in the brain‐expressed tryptophan hydroxylase gene (<i>TPH2</i>) |
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| Ordered‐subset analysis of savant skills in autism for 15q11‐q13 |
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| Association analysis of monoamine genes with measures of depression and anxiety in a selected community sample of siblings |
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| Klinefelter's syndrome (XXY) as a genetic model for psychotic disorders |
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| Further analysis of microsatellite marker in the <i>BDNF</i> gene |
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| A meta‐analysis of the MTHFR C677T polymorphism and schizophrenia risk |
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| A functional glutathione<i>S</i>‐transferase P1 gene polymorphism is associated with methamphetamine‐induced psychosis in Japanese population |
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| Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease |
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| Association between the serotonin transporter gene and alcohol consumption in social drinkers |
|
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✓ |
✓ |
ethnically homogenous |
| Superior verbal ability and nonverbal learning disability in a child with a novel 17p12p13.1 deletion |
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| Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: Preferential transmission of the MAO‐A 941G allele to affected chil |
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✓ |
✓ |
Irish; Irish population |
| Association analysis of transcripts from the bipolar susceptibility locus on chromosome 4q35, exclusion of a pathogenic role for eight positional candidate genes |
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| Hypermethylation of the reelin (<i>RELN</i>) promoter in the brain of schizophrenic patients: A preliminary report |
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| Serotonin receptor 2C (HTR2C) and schizophrenia: Examination of possible medication and genetic influences on expression levels |
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| Support for association between ADHD and two candidate genes: <i>NET1</i> and <i>DRD1</i> |
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| Association between BDNF val<sup>66</sup> met genotype and episodic memory |
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|
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| DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: No evidence for association |
|
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|
|
| No association of GSK3β gene (<i>GSK3B</i>) with Japanese schizophrenia |
|
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|
|
✓ |
✓ |
Japanese |
| The serotonin transporter gene as a QTL for ADHD |
|
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|
|
| Linkage evidence of schizophrenia to loci near neuregulin 1 gene on chromosome 8p21 in Taiwanese families |
|
✓ |
|
|
|
|
✓ |
✓ |
Taiwanese |
| A48G polymorphism in the D<sub>1</sub> receptor genes associated with bipolar I disorder |
|
|
|
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|
|
✓ |
✓ |
exclusively Sardinian descent |
| Association between the DRD2 A1 allele and opium addiction in the Iranian population |
|
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|
|
| The Washington University Twin Study of alcoholism |
|
|
|
✓ |
|
✓ |
|
|
males of Northern and Western European ancestry |
| Genetic linkage of bipolar disorder to chromosome 6q22 is a consistent finding in Portuguese subpopulations and may generalize to broader populations |
|
✓ |
|
|
|
|
✓ |
✓ |
East Asian; African-American; Portuguese; PIC (Portuguese island collection) |
| Taiwan schizophrenia linkage study: The field study |
|
|
|
|
|
|
✓ |
✓ |
Taiwanese Chinese |
| Evidence for the gamma‐amino‐butyric acid type B receptor 1 (<i>GABBR1</i>) gene as a susceptibility factor in obsessive‐compulsive disorder |
|
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| Weight gain associated with the −759C/T polymorphism of the 5HT2C receptor and olanzapine |
|
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|
|
| Human brain derived neurotrophic factor (<i>BDNF</i>) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease |
|
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|
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| Assessing the validity of blood‐based gene expression profiles for the classification of schizophrenia and bipolar disorder: A preliminary report |
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| Familial cognitive deficits in schizophrenia |
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|
|
| Serotonin transporter intron 2 polymorphism associated with rigid‐compulsive behaviors in Dutch individuals with pervasive developmental disorder |
|
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|
|
✓ |
✓ |
Dutch |
| Identification and characterization of human NR4A2 polymorphisms in attention deficit hyperactivity disorder |
|
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|
|
| Suicide attempt and basic mechanisms in neural conduction: Relationships to the <i>SCN8A</i> and <i>VAMP4</i> genes |
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|
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| Serotonin transporter promoter polymorphism and monoamine oxidase type A VNTR allelic variants together influence alcohol binge drinking risk in young women |
|
✓ |
|
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|
|
| Exclusion of non‐synonymous SNPs and a polyglutamine tract in SMRT/N‐CoR2 as common deleterious mutation for bipolar disorder in the Sagnenay‐Lac‐St‐Jean population |
|
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|
|
| No association between 12 dopaminergic genes and schizophrenia in a large Dutch sample |
|
✓ |
|
|
|
|
✓ |
✓ |
Dutch ancestry |
| Pleiotropic effect of the TPH A779C polymorphism on nicotine dependence and personality |
|
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|
|
| Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease |
|
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|
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| GRIN1 locus may modify the susceptibility to seizures during alcohol withdrawal |
|
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| Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases |
|
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|
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| Clozapine‐induced weight gain associated with the 5HT2C receptor −759C/T polymorphism |
|
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|
|
| Defining the ends of Parkin exon 4 deletions in two different families with Parkinson's disease |
|
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| Linkage disequilibrium analysis in the LOC93081‐KDELC1‐BIVM region on 13q in bipolar disorder |
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|
|
| Interaction of polymorphisms in the genes encoding interleukin‐6 and estrogen receptor beta on the susceptibility to Parkinson's disease |
|
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|
|
| A family study of obsessive‐compulsive disorder with pediatric probands |
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| Familial aggregation of schizophrenia‐spectrum disorders and obsessive‐compulsive associated disorders in schizophrenia probands with and without OCD |
|
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|
|
| A family based study of catechol‐<i>O</i>‐methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD) |
|
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|
|
| Meta‐analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence |
|
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|
|
|
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|
|
| Family history influences age of onset in bipolar I disorder in females but not in males |
|
|
|
|
|
|
✓ |
✓ |
Romanian; German |
| Site‐specific cytosine methylation in S‐COMT promoter in 31 brain regions with implications for studies involving schizophrenia |
|
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